GPR12

Description		G protein-coupled receptor 12
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Phosphatidylcholine Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs		Cannabidiol Medical Cannabis Nabiximols
Diseases
GWAS		Adult body size ( 32376654) Eosinophilic esophagitis ( 34506852) Mortality in sepsis ( 27639821) Nose morphology ( 29921221)
Novel Interacting Genes		1 novel interacting genes: FLT3
Interacting Genes		1 interacting genes: APP
Entrez ID		2835
HPRD ID		15978
Ensembl ID		ENSG00000132975
Uniprot IDs		A8K2F5 B4DG25 P47775
PDB IDs		7Y3G
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Positive Regulation Of Phosphate Metabolic Process Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Endosome To Plasma Membrane Transport Vesicle Hemopoiesis Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Receptor Complex Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Endoplasmic Reticulum Lumen Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Pro-B Cell Differentiation Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of MAPK Cascade NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Vascular Endothelial Growth Factor Receptor Activity Common Myeloid Progenitor Cell Proliferation Myeloid Progenitor Cell Differentiation Phosphatidylinositol 3-kinase Activator Activity Heparan Sulfate Binding Signaling Receptor Activator Activity Regulation Of Phosphorus Metabolic Process Peptidase Activator Activity Response To Peptide Response To Cytokine
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