BCL9L

Gene Name		B-cell CLL/lymphoma 9-like
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Transcription Coactivator Activity Beta-catenin Binding
	Biological Process	Transcription, DNA-templated Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Cell Morphogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Somatic Stem Cell Maintenance Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Canonical Wnt Signaling Pathway
Pathways		misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation formation of the beta-catenin:TCF transactivating complex XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: CTNNB1
Entrez ID		283149
HPRD ID		10612
Ensembl ID
Uniprot IDs		Q86UU0
PDB IDs		2XB1
Enriched GO Terms of Interacting Partners?		Schwann Cell Proliferation Negative Regulation Of Mitotic Cell Cycle, Embryonic Cellular Response To Insulin-like Growth Factor Stimulus Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Positive Regulation Of Determination Of Dorsal Identity Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Lung Induction Central Nervous System Vasculogenesis Trachea Formation Cellular Response To Indole-3-methanol Regulation Of Centromeric Sister Chromatid Cohesion Renal Vesicle Formation Regulation Of Mitotic Cell Cycle, Embryonic Negative Regulation Of Protein Sumoylation Positive Regulation Of Branching Involved In Lung Morphogenesis Regulation Of Secondary Heart Field Cardioblast Proliferation Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Branching Involved In Lung Morphogenesis Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Fungiform Papilla Formation Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Establishment Of Blood-brain Barrier Fungiform Papilla Morphogenesis Glial Cell Proliferation Metanephric Renal Vesicle Morphogenesis Endothelial Tube Morphogenesis Renal Vesicle Morphogenesis Sympathetic Ganglion Development Endodermal Cell Fate Commitment Fungiform Papilla Development Regulation Of Sister Chromatid Cohesion Neural Plate Development Positive Regulation Of Endothelial Cell Differentiation Mesenchymal Cell Proliferation Lung-associated Mesenchyme Development Mesenchymal To Epithelial Transition Epithelial Cell Differentiation Involved In Prostate Gland Development Trachea Morphogenesis Positive Regulation Of Glycoprotein Biosynthetic Process Genitalia Morphogenesis
Tagcloud ?		activates catenin circuit conserved context critically directly domains encode evolutionarily eye generated hd1 hd2 lack lacking lens master mediate pax6 probe pygo pygopus regulator roles uncover wnt