GPR6

Description		G protein-coupled receptor 6
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Sphingosine-1-phosphate Receptor Activity
	Biological Process	Sphingosine-1-phosphate Receptor Signaling Pathway Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Metabolite levels ( 23823483)
Novel Interacting Genes		1 novel interacting genes: FOXO3
Interacting Genes
Entrez ID		2830
HPRD ID		02775
Ensembl ID		ENSG00000146360
Uniprot IDs		F1DAM6 P46095
PDB IDs		8T1V 8T1W 8TF5 8TYW
Enriched GO Terms of Interacting Partners?		Mitochondrial Transcription Factor Activity Positive Regulation Of Muscle Atrophy Response To Water-immersion Restraint Stress Antral Ovarian Follicle Growth Initiation Of Primordial Ovarian Follicle Growth Cellular Response To Corticosterone Stimulus Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death RNA Polymerase II Transcription Repressor Complex Mitochondrial Transcription Ovulation From Ovarian Follicle Cellular Response To Mineralocorticoid Stimulus Ovulation Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Response To Corticosterone Oocyte Maturation Response To Immobilization Stress Positive Regulation Of Regulatory T Cell Differentiation Brain Morphogenesis Neuronal Stem Cell Population Maintenance Positive Regulation Of Endothelial Cell Apoptotic Process Ovulation Cycle Process Response To Nerve Growth Factor Transcription Coregulator Binding Positive Regulation Of Erythrocyte Differentiation Response To Mineralocorticoid Regulation Of Regulatory T Cell Differentiation Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Reactive Oxygen Species Biosynthetic Process Response To Dexamethasone Mitochondrial RNA Metabolic Process Cellular Response To Nerve Growth Factor Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Response To Glucose Starvation Cellular Response To Amyloid-beta Regulation Of Erythrocyte Differentiation Regulation Of Endothelial Cell Apoptotic Process Cellular Response To Glucose Stimulus Response To Fatty Acid Positive Regulation Of Reactive Oxygen Species Metabolic Process Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Glucocorticoid Stimulus Positive Regulation Of MiRNA Metabolic Process Cellular Response To Corticosteroid Stimulus Positive Regulation Of MiRNA Transcription Response To Amyloid-beta Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Differentiation Regulation Of MiRNA Transcription Cellular Response To Carbohydrate Stimulus Chromatin DNA Binding
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