GPM6B

Description		glycoprotein M6B
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Myelin Sheath Membrane Raft
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath
	Biological Process	Ossification Nervous System Development Protein Transport Central Nervous System Myelination Cell Differentiation Positive Regulation Of Bone Mineralization Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Serotonin Uptake Regulation Of Focal Adhesion Assembly Axon Development Extracellular Matrix Assembly Negative Regulation Of Protein Localization To Cell Surface
Pathways
Drugs
Diseases
GWAS		Delayed reward discounting ( 29230059) Glaucoma (primary open-angle) ( 33627673)
Interacting Genes		7 interacting genes: CLN8 EGFR ERBB2 ERGIC3 MTNR1B SLC6A4 STX1A
Entrez ID		2824
HPRD ID		02082
Ensembl ID		ENSG00000046653
Uniprot IDs		B7Z613 Q13491 Q59FD5
PDB IDs
Enriched GO Terms of Interacting Partners?		ERBB2-EGFR Signaling Pathway Regulation Of Protein Localization Neurotransmitter Transport Presynaptic Membrane Neurotransmitter Reuptake Regulation Of Establishment Of Protein Localization ERBB2 Signaling Pathway Neurotransmitter Uptake Learning Or Memory Cellular Response To Epidermal Growth Factor Stimulus Transmembrane Receptor Protein Tyrosine Kinase Activity Cognition Response To Epidermal Growth Factor Negative Regulation Of Apoptotic Process Endosome Membrane Negative Regulation Of Programmed Cell Death Neuron Differentiation Basal Plasma Membrane Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Multivesicular Body, Internal Vesicle Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Regulation Of Thalamus Size Positive Regulation Of Serotonin Secretion Cocaine Binding Myosin Head/neck Binding Regulation Of Membrane Potential Regulation Of Protein Transport Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Kinase Binding Ruffle Membrane Shc-EGFR Complex Negative Regulation Of Multicellular Organismal Process Associative Learning Somatic Motor Neuron Differentiation Glutamate Reuptake Retinal Rod Cell Apoptotic Process ERBB3:ERBB2 Complex Serotonergic Synapse Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Retrograde Transporter Complex, Golgi To ER Response To Estradiol Regulation Of Cellular Localization Localization Within Membrane Amino Acid Transport Regulation Of Nervous System Process Positive Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Receptor Activity Protein Tyrosine Kinase Activity
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