GNAT2

Description		G protein subunit alpha transducin 2
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Heterotrimeric G-protein Complex Plasma Membrane Membrane Photoreceptor Outer Segment Membrane Cell Projection Synapse
	Molecular Function	Nucleotide Binding G Protein-coupled Receptor Binding GTPase Activity GTP Binding G Protein-coupled Photoreceptor Activity Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding
	Biological Process	Cell Morphogenesis Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Visual Perception Phototransduction Visual Behavior Intracellular Protein Localization Response To UV Response To Light Stimulus Detection Of Light Stimulus Detection Of Visible Light Response To Light Intensity Gene Expression Dopamine Metabolic Process Retinal Cone Cell Differentiation Camera-type Eye Development Retinal Cone Cell Development Tissue Remodeling Homeostasis Of Number Of Retina Cells Detection Of Light Stimulus Involved In Visual Perception L-glutamate Import Retinal Rod Cell Differentiation Neural Tissue Regeneration Background Adaptation Reactive Gliosis Cone Retinal Bipolar Cell Differentiation
Pathways		Ca2+ pathway Ca2+ pathway G alpha (i) signalling events
Drugs
Diseases		Achromatopsia; Rod monochromacy
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 25673413 26961502 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Hand grip strength ( 29691431) Hip circumference ( 25673412) Major depressive disorder ( 20125088) Obesity ( 23563607)
Interacting Genes		2 interacting genes: ADRB2 APP
Entrez ID		2780
HPRD ID		00762
Ensembl ID		ENSG00000134183
Uniprot IDs		P19087 Q5T697
PDB IDs		6N84 6N85
Enriched GO Terms of Interacting Partners?		Neuronal Dense Core Vesicle Positive Regulation Of CAMP/PKA Signal Transduction Positive Regulation Of Excitatory Postsynaptic Potential Ionotropic Glutamate Receptor Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Glutamate Receptor Signaling Pathway Ligand-gated Ion Channel Signaling Pathway Cellular Response To Amyloid-beta Modulation Of Excitatory Postsynaptic Potential Response To Amyloid-beta Regulation Of Multicellular Organism Growth Regulation Of Nervous System Process Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Mini Excitatory Postsynaptic Potential Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Receptor Complex Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Beta2-adrenergic Receptor Activity Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Early Endosome Regulation Of Developmental Growth Beta-adrenergic Receptor Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Psychosocial Stress Enzyme Binding Norepinephrine Binding Positive Regulation Of Lipophagy Regulation Of Metal Ion Transport AMPA Selective Glutamate Receptor Signaling Pathway Regulation Of Monoatomic Ion Transport Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle
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