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BHLHE22

Description basic helix-loop-helix family member e22
Image No pdb structure
GO Annotations Cellular Component
  • Chromatin
  • Nucleus
Molecular Function
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • Protein Dimerization Activity
  • E-box Binding
  • Sequence-specific Double-stranded DNA Binding
Biological Process
  • Nervous System Development
  • Sensory Organ Development
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Axon Development
Pathways
  • Regulation of CDH11 gene transcription
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Alcohol consumption ( 31358974)
  • Automobile speeding propensity ( 30643258)
  • Body mass index ( 26426971)
  • Chronotype ( 30696823)
  • General risk tolerance (MTAG) ( 30643258)
  • Neurociticism ( 29500382)
Interacting Genes 1 interacting genes: OTUD3
Entrez ID 27319
HPRD ID 16551
Ensembl ID ENSG00000180828
Uniprot IDs B4DF88 Q8NFJ8
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Protein K6-linked Deubiquitination
  • Protein K27-linked Deubiquitination
  • Protein K11-linked Deubiquitination
  • Protein K48-linked Deubiquitination
  • Rescue Of Stalled Ribosome
  • Ribosome Disassembly
  • Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
  • Translational Elongation
  • Organelle Disassembly
  • Energy Homeostasis
  • Cysteine-type Deubiquitinase Activity
  • Protein Deubiquitination
  • Protein Modification By Small Protein Removal
  • Cysteine-type Peptidase Activity
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© Madhavi K. Ganapathiraju 2012-2025