DKK2

Gene Name		dickkopf WNT signaling pathway inhibitor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space
	Molecular Function
	Biological Process	Multicellular Organismal Development Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation negative regulation of TCF-dependent signaling by WNT ligand antagonists XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: LRP6
Entrez ID		27123
HPRD ID		05658
Ensembl ID		ENSG00000155011
Uniprot IDs		Q9UBU2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Canonical Wnt Signaling Pathway Involved In Cardiac Neural Crest Cell Differentiation Involved In Heart Development Negative Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure Negative Regulation Of Planar Cell Polarity Pathway Involved In Outflow Tract Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Pericardium Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Right Atrium Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Muscle Tissue Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Ventricular Septum Morphogenesis External Genitalia Morphogenesis Wnt Signaling Pathway Involved In Forebrain Neuroblast Division Receptor-mediated Endocytosis Of Low-density Lipoprotein Particle Involved In Cholesterol Transport Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure Canonical Wnt Signaling Pathway Involved In Neural Crest Cell Differentiation Axis Elongation Involved In Somitogenesis Neural Crest Formation Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Negative Regulation Of Wnt Signaling Pathway Involved In Heart Development Pericardium Morphogenesis Mammary Placode Formation Forebrain Radial Glial Cell Differentiation Wnt Signaling Pathway Involved In Somitogenesis Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Negative Regulation Of Smooth Muscle Cell Apoptotic Process Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Intracellular Cholesterol Transport Intracellular Sterol Transport Trachea Cartilage Morphogenesis Radial Glial Cell Differentiation Primitive Streak Formation Negative Regulation Of Non-canonical Wnt Signaling Pathway Formation Of Radial Glial Scaffolds Mammary Gland Formation Midbrain-hindbrain Boundary Development Response To Folic Acid Embryonic Retina Morphogenesis In Camera-type Eye Regulation Of Smooth Muscle Cell Apoptotic Process Trachea Cartilage Development Thalamus Development Convergent Extension Forebrain Neuroblast Division Positive Regulation Of Bone Resorption Cellular Response To Cholesterol Cell Migration Involved In Gastrulation Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Dopaminergic Neuron Differentiation Trachea Morphogenesis Cellular Response To Sterol Genitalia Morphogenesis Cartilage Morphogenesis Rostrocaudal Neural Tube Patterning
Tagcloud ?		abcb1b administrated brosis colla1 corroborated dkk1 dkk3 dkk4 fi frizzled frzb fz1 fz5 fz7 nano nephrotoxicity osteopontin sfrp tio2 wnt1 wnt10a wnt11 wnt2 wnt3 wnt4 wnt5a wnt6 wnt7a wnt9a