PDE7B

Gene Name		phosphodiesterase 7B
Image
Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	3',5'-cyclic-AMP Phosphodiesterase Activity Metal Ion Binding
	Biological Process	CAMP Catabolic Process Signal Transduction Synaptic Transmission
Pathways		Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events
Drugs		Dyphylline Ketotifen
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Phosphorus levels ( 20558539)
Protein-protein Interactions		1 interactors: SRPK2
Entrez ID		27115
HPRD ID		06870
Ensembl ID		ENSG00000171408
Uniprot IDs		A1E5M1 Q9NP56
PDB IDs		1LXW
Enriched GO Terms of Interacting Partners?		Nuclear Speck Organization Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Positive Regulation Of Neuron Apoptotic Process Spliceosomal Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Positive Regulation Of Neuron Death Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleus Organization Regulation Of Viral Process Ribonucleoprotein Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Neuron Apoptotic Process Positive Regulation Of Cell Cycle Regulation Of Neuron Death Ribonucleoprotein Complex Biogenesis Angiogenesis RNA Splicing
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