SIGLEC7

Gene Name		sialic acid binding Ig-like lectin 7
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Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane
	Molecular Function	Receptor Activity Carbohydrate Binding
	Biological Process	Cell Adhesion
Pathways
Drugs		Beta-D-Mannose Alpha-D-Mannose 2-(Acetylamino)-2-Deoxy-a-D-Glucopyranose
Diseases
GWAS
Protein-protein Interactions		3 interactors: GRB2 PTPN11 TRAF4
Entrez ID		27036
HPRD ID		05102
Ensembl ID		ENSG00000168995
Uniprot IDs		Q9Y286
PDB IDs		1NKO 1O7S 1O7V 2DF3 2G5R 2HRL
Enriched GO Terms of Interacting Partners?		Regulation Of MAPK Cascade T Cell Costimulation Phosphatidylinositol-mediated Signaling Insulin Receptor Signaling Pathway Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of T Cell Activation Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Phosphorus Metabolic Process Neurotrophin Signaling Pathway Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion Abortive Mitotic Cell Cycle Negative Regulation Of Glucocorticoid Secretion Activation Of Protein Kinase Activity Fc Receptor Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Intracellular Signal Transduction Response To Insulin Regulation Of T Cell Activation Positive Regulation Of Cell Activation Intracellular Signal Transduction Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Negative Regulation Of Cell Adhesion Mediated By Integrin Axon Guidance Regulation Of Lymphocyte Activation Blood Coagulation Hemostasis Positive Regulation Of MAPK Cascade Response To Peptide Hormone Positive Regulation Of Protein Kinase Activity Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Cellular Response To Organonitrogen Compound Positive Regulation Of Protein Homodimerization Activity Regulation Of Growth Hormone Secretion See more
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