GJA4

Description		gap junction protein alpha 4
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Gap Junction Connexin Complex Membrane Anchoring Junction
	Molecular Function	Gap Junction Channel Activity Protein Binding
	Biological Process	Blood Vessel Development Cell-cell Junction Assembly Cell Communication Cell-cell Signaling Transmembrane Transport
Pathways		Gap junction assembly
Drugs
Diseases
GWAS		Formal thought disorder in schizophrenia ( 22648509) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Novel Interacting Genes		1 novel interacting genes: DNALI1
Interacting Genes		5 interacting genes: CD81 MS4A13 OPRM1 SLC29A2 TMEM86B
Entrez ID		2701
HPRD ID		08509
Ensembl ID		ENSG00000187513
Uniprot IDs		P35212
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Myoblast Fusion Involved In Skeletal Muscle Regeneration Cytidine Transmembrane Transporter Activity Uracil Transmembrane Transport Thymine Transport Inosine Transport Pyrimidine Nucleobase Transmembrane Transport Nucleobase Transmembrane Transporter Activity Cytidine Transport Uracil Transmembrane Transporter Activity Purine Nucleoside Transmembrane Transport Guanine Transmembrane Transporter Activity Guanine Transport Guanine Transmembrane Transport Adenosine Transport Hypoxanthine Transport Purine Nucleoside Transmembrane Transporter Activity Regulation Of NMDA Receptor Activity Cellular Response To Morphine Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity D-lysine 5,6-aminomutase Activity Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Humoral Immune Response Mediated By Circulating Immunoglobulin Uridine Transmembrane Transport Adenine Transmembrane Transporter Activity Pyrimidine Nucleoside Transport Nucleoside Transmembrane Transporter Activity Uridine Transmembrane Transporter Activity MHC Class II Protein Binding Osteoclast Fusion Nucleoside Transmembrane Transport Adenine Transport Nucleoside Transport Pyrimidine Nucleobase Transport Positive Regulation Of Protein Catabolic Process In The Vacuole Purine Nucleobase Transmembrane Transport G Protein-coupled Opioid Receptor Activity Positive Regulation Of B Cell Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Basolateral Plasma Membrane Positive Regulation Of T-helper 2 Cell Cytokine Production Tetraspanin-enriched Microdomain G Protein-coupled Opioid Receptor Signaling Pathway Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
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