FGF22

Description		fibroblast growth factor 22
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleolus Cytoplasm Golgi Apparatus Cell Surface Postsynapse Glutamatergic Synapse GABA-ergic Synapse Extrinsic Component Of Postsynaptic Density Membrane
	Molecular Function	Fibroblast Growth Factor Receptor Binding Growth Factor Activity
	Biological Process	Positive Regulation Of Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Neurogenesis Cell Differentiation Regulation Of Cell Migration Positive Regulation Of MAPK Cascade Regulation Of Synapse Maturation Trans-synaptic Signaling
Pathways		PI3K Cascade PIP3 activates AKT signaling FGFR1b ligand binding and activation FGFR2b ligand binding and activation Activated point mutants of FGFR2 Constitutive Signaling by Aberrant PI3K in Cancer Phospholipase C-mediated cascade: FGFR1 Phospholipase C-mediated cascade; FGFR2 Downstream signaling of activated FGFR1 SHC-mediated cascade:FGFR1 PI-3K cascade:FGFR1 FRS-mediated FGFR1 signaling PI-3K cascade:FGFR2 SHC-mediated cascade:FGFR2 FRS-mediated FGFR2 signaling Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Signaling by FGFR2 in disease FGFRL1 modulation of FGFR1 signaling RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases
GWAS
Interacting Genes		1 interacting genes: PTX3
Entrez ID		27006
HPRD ID		05784
Ensembl ID		ENSG00000070388
Uniprot IDs		K7ELB9 Q9HCT0
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation By Host Of Viral Glycoprotein Metabolic Process (1->3)-beta-D-glucan Binding Ovarian Cumulus Expansion Complement Component C1q Complex Binding Virion Binding Negative Regulation Of Glycoprotein Metabolic Process Opsonization Host-mediated Suppression Of Viral Proces Response To Yeast Host-mediated Suppression Of Symbiont Invasion Ovulation Cycle Process Positive Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Specific Granule Lumen Tertiary Granule Lumen Response To Fungus Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Phagocytosis Host-mediated Perturbation Of Viral Process Negative Regulation Of Viral Process Regulation Of Phagocytosis Host-mediated Perturbation Of Symbiont Process Modulation Of Process Of Another Organism Regulation Of Viral Process Positive Regulation Of Endocytosis Extracellular Matrix Organization Rhythmic Process Extracellular Structure Organization Regulation Of Endocytosis
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