GFRA3

Description		GDNF family receptor alpha 3
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GO Annotations	Cellular Component	Cytosol Plasma Membrane External Side Of Plasma Membrane Membrane Extrinsic Component Of Membrane Receptor Complex Side Of Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Axon Guidance Receptor Activity Glial Cell-derived Neurotrophic Factor Receptor Activity Signaling Receptor Activity
	Biological Process	Neuron Migration Signal Transduction Nervous System Development Axon Guidance Peripheral Nervous System Development Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Sympathetic Nervous System Development Neuron Development
Pathways		RAF/MAP kinase cascade RET signaling
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Autism spectrum disorder or schizophrenia ( 28540026) Immune reponse to smallpox (secreted IL-12p40) ( 22610502) QT interval ( 24952745) Schizophrenia ( 25056061)
Novel Interacting Genes		1 novel interacting genes: COL6A3
Interacting Genes		1 interacting genes: ARTN
Entrez ID		2676
HPRD ID		10420
Ensembl ID		ENSG00000146013
Uniprot IDs		O60609
PDB IDs		2GH0 6Q2S
Enriched GO Terms of Interacting Partners?		Collagen Type VI Trimer Glial Cell-derived Neurotrophic Factor Receptor Binding Peyer's Patch Morphogenesis Lymphocyte Migration Into Lymphoid Organs Induction Of Positive Chemotaxis Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Positive Regulation Of Positive Chemotaxis Peripheral Nervous System Development Extracellular Matrix Structural Constituent Conferring Tensile Strength Neuroblast Proliferation Extracellular Space Lymphocyte Migration Receptor Tyrosine Kinase Binding Neuron Apoptotic Process Extracellular Region Peptidase Inhibitor Activity Muscle Organ Development Sarcolemma Muscle Structure Development Collagen Trimer Serine-type Endopeptidase Inhibitor Activity Extracellular Vesicle Response To Monosaccharide Response To Glucose Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Neural Precursor Cell Proliferation Positive Regulation Of Chemotaxis Mononuclear Cell Migration Response To UV Response To Carbohydrate Growth Factor Activity
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