FBXO9

Description		F-box protein 9
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Apoptotic Process Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of TOR Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Fat Cell Differentiation Protein K48-linked Ubiquitination Positive Regulation Of Epithelial Cell Apoptotic Process
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Staphylococcus aureus nasal carriage (intermittent) ( 26569114)
Interacting Genes		2 interacting genes: CALM1 SKP1
Entrez ID		26268
HPRD ID		16434
Ensembl ID		ENSG00000112146
Uniprot IDs		Q9UK97
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrion-endoplasmic Reticulum Membrane Tethering Positive Regulation Of Sequestering Of Calcium Ion Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Negative Regulation Of Voltage-gated Calcium Channel Activity Adenylate Cyclase Activator Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Autophagosome Membrane Docking Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity F-box Domain Binding Cul7-RING Ubiquitin Ligase Complex Ubiquitin Ligase Complex Scaffold Activity Titin Binding Centrosome Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Ubiquitin Ligase Activator Activity Regulation Of Voltage-gated Calcium Channel Activity Detection Of Calcium Ion Calcium Channel Inhibitor Activity Regulation Of Cell Communication By Electrical Coupling Negative Regulation Of Transporter Activity Protein Phosphatase Activator Activity Cellular Response To Interferon-beta Catalytic Complex Presynaptic Cytosol Calcium Channel Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Cardiac Muscle Cell Action Potential Calyx Of Held Calcineurin-mediated Signaling Maintenance Of Protein Location In Nucleus PcG Protein Complex Cullin Family Protein Binding Molecular Function Activator Activity Positive Regulation Of Epithelial Cell Apoptotic Process Myelin Sheath Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Response To Interferon-beta Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Calcium Ion Transmembrane Transport Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Presynaptic Endocytosis Spindle Microtubule Substantia Nigra Development Maintenance Of Protein Localization In Organelle Positive Regulation Of Receptor Signaling Pathway Via STAT Calcium Channel Regulator Activity
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