ZBTB20

Description		zinc finger and BTB domain containing 20
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process Negative Regulation Of Gene Expression Positive Regulation Of Interferon-beta Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Glycolytic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Lipid Biosynthetic Process Lipid Homeostasis Cellular Response To Glucose Stimulus
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Fish- and plant-related diet ( 32066663) Gastric cancer ( 22037551 31383772) General risk tolerance (MTAG) ( 30643258) Haemorrhoidal disease ( 33888516) HDL cholesterol levels ( 32203549) HIV-1 viral setpoint ( 26039976) Mitochondrial DNA levels ( 25240745) Mucinous adenocarcinoma in colorectal cancer ( 29942513) Oily fish consumption ( 32066663) Platelet count ( 32888494) Plateletcrit ( 32888494) Pork consumption ( 32066663) Postoperative atrial fibrillation after cardiac surgery ( 30678657) Seasonality and depression ( 30217971) Serum alkaline phosphatase levels ( 33547301) Smoking initiation ( 33082346) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure ( 30224653) Type 2 diabetes ( 26818947 32499647) Urate levels in obese individuals ( 25811787) Youthful appearance (self-reported) ( 32339537)
Novel Interacting Genes		1 novel interacting genes: CD47
Interacting Genes		4 interacting genes: CDK2 NR3C1 PPARG TMEM132D
Entrez ID		26137
HPRD ID		05822
Ensembl ID		ENSG00000181722
Uniprot IDs		B2RCW4 Q9HC78
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Interleukin-12 Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Regulation Of MiRNA Transcription Nuclear Receptor-mediated Signaling Pathway Nuclear Glucocorticoid Receptor Activity Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription Nuclear Receptor Activity Negative Regulation Of Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Positive Regulation Of Adiponectin Secretion Positive Regulation Of Chromatin Organization Cyclin-dependent Protein Kinase Activity Cyclin A2-CDK2 Complex Cyclin E1-CDK2 Complex Hormone-mediated Signaling Pathway Myeloid Leukocyte Differentiation Protein Binding Involved In Heterotypic Cell-cell Adhesion Positive Regulation Of Monocyte Extravasation ATP Export Response To Interleukin-12 Thrombospondin Receptor Activity X Chromosome Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Cellular Response To Oxygen-containing Compound Histone Kinase Activity Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Nuclear Receptor-mediated Corticosteroid Signaling Pathway Steroid Hormone Binding Intracellular Receptor Signaling Pathway Positive Regulation Of Lipoprotein Transport Arachidonate Binding Negative Regulation Of Mitochondrial Fission Prostaglandin Receptor Activity DNA Binding Domain Binding Fibrinogen Binding Protection From Non-homologous End Joining At Telomere Response To Cortisol Myeloid Cell Differentiation Negative Regulation Of Type II Interferon-mediated Signaling Pathway LBD Domain Binding Mammary Gland Duct Morphogenesis Microglia Differentiation DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Regulation Of Heterochromatin Formation
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