SIPA1L1

Gene Name		signal-induced proliferation-associated 1 like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytoplasm Cytoskeleton Postsynaptic Density Cell Junction Dendritic Spine Postsynaptic Membrane
	Molecular Function	Molecular_function GTPase Activator Activity Ephrin Receptor Binding
	Biological Process	Biological_process Actin Cytoskeleton Reorganization Regulation Of Rap GTPase Activity Activation Of Rap GTPase Activity Ephrin Receptor Signaling Pathway Regulation Of Synaptic Plasticity Regulation Of Axonogenesis Regulation Of Dendritic Spine Morphogenesis
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Ventricular conduction ( 21076409)
Protein-protein Interactions		3 interactors: CEBPE DLG4 NRXN1
Entrez ID		26037
HPRD ID		11559
Ensembl ID		ENSG00000197555
Uniprot IDs		F5GYF8 J3KP19 O43166
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Grooming Behavior Receptor Localization To Synapse Vocalization Behavior Protein Localization To Synapse Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Postsynaptic Membrane Organization Positive Regulation Of Excitatory Postsynaptic Membrane Potential Social Behavior Positive Regulation Of Membrane Potential Receptor Clustering Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Synapse Assembly Neuromuscular Process Controlling Balance Positive Regulation Of Synaptic Transmission Membrane Depolarization Regulation Of Receptor Activity Neuromuscular Process Learning Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Synapse Organization Regulation Of Behavior Vesicle Localization Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Gephyrin Clustering Synaptic Vesicle Clustering Learning Or Memory Regulation Of Membrane Potential Cognition Neuronal Signal Transduction Response To External Stimulus Regulation Of Synaptic Transmission N-methyl-D-aspartate Receptor Clustering Vocal Learning Negative Regulation Of Filopodium Assembly Postsynaptic Membrane Assembly Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Protein Localization To Membrane Maintenance Of Apical/basal Cell Polarity Synapse Maturation Axon Guidance Organelle Localization Regulation Of Ion Transmembrane Transport Negative Regulation Of Receptor Internalization Presynaptic Membrane Assembly Postsynaptic Density Protein 95 Clustering
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