LRIG1

Gene Name		leucine-rich repeats and immunoglobulin-like domains 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane
	Molecular Function
	Biological Process	Sensory Perception Of Sound Otolith Morphogenesis Innervation
Pathways		Signaling by EGFR Signaling by EGFR in Cancer Signaling by Ligand-Responsive EGFR Variants in Cancer Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by EGFRvIII in Cancer
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065) Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065) Carotid intima media thickness ( 21909108) Renal function-related traits (BUN) ( 22797727) Ventricular conduction ( 21076409)
Protein-protein Interactions		1 interactors: CBL
Entrez ID		26018
HPRD ID		10057
Ensembl ID		ENSG00000144749
Uniprot IDs		Q96JA1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Endocytosis Cellular Response To Fibroblast Growth Factor Stimulus Response To Transforming Growth Factor Beta Response To Fibroblast Growth Factor Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Tagcloud ?		adjunct biopsies cadherin cervical cin ck10 contraceptive correlates epithelium estradiol favorable habits hormonal hormones influences intraepithelial invasive lrig2 lrig3 menopausal neoplasia p16 precancerous progestogenic retinoblastoma smoking stained suppressors