TKFC

Description		triokinase and FMN cyclase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Extracellular Exosome
	Molecular Function	Nucleotide Binding Catalytic Activity Glycerone Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Lyase Activity FAD-AMP Lyase (cyclizing) Activity Metal Ion Binding Triokinase Activity
	Biological Process	Carbohydrate Metabolic Process Glycerol Metabolic Process Glycerol Catabolic Process Negative Regulation Of MDA-5 Signaling Pathway Regulation Of Innate Immune Response Carbohydrate Phosphorylation Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate
Pathways		DDX58/IFIH1-mediated induction of interferon-alpha/beta Fructose catabolism SARS-CoV-1 activates/modulates innate immune responses SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: TIMM10
Interacting Genes		1 interacting genes: SDCBP
Entrez ID		26007
HPRD ID		13180
Ensembl ID		ENSG00000149476
Uniprot IDs		A0A140VJH7 Q3LXA3
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization To Membrane Protein Targeting Interleukin-5 Receptor Complex Interleukin-5 Receptor Binding Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Regulation Of Extracellular Exosome Assembly Mitochondrial Intermembrane Space Chaperone Complex TIM22 Mitochondrial Import Inner Membrane Insertion Complex Localization Within Membrane Substrate-dependent Cell Migration, Cell Extension Negative Regulation Of Receptor Internalization Positive Regulation Of Exosomal Secretion Membrane Insertase Activity TIM23 Mitochondrial Import Inner Membrane Translocase Complex Regulation Of Exosomal Secretion Protein Insertion Into Mitochondrial Inner Membrane Cytoskeletal Anchor Activity Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Receptor-mediated Endocytosis Establishment Of Protein Localization To Mitochondrial Membrane Protein Targeting To Mitochondrion Protein Insertion Into Mitochondrial Membrane Frizzled Binding Inner Mitochondrial Membrane Organization Protein Sequestering Activity Establishment Of Protein Localization
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