TSKU

Description		tsukushi, small leucine rich proteoglycan
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Binding Transforming Growth Factor Beta Binding
	Biological Process	Growth Plate Cartilage Chondrocyte Development Immune Response Transforming Growth Factor Beta Receptor Signaling Pathway Nervous System Development Cholesterol Metabolic Process Anatomical Structure Morphogenesis Regulation Of Gene Expression Negative Regulation Of Neuron Projection Development Corpus Callosum Morphogenesis Lateral Ventricle Development Hippocampus Development Anterior Commissure Morphogenesis Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Cholesterol Efflux Wound Healing Cholesterol Homeostasis Positive Regulation Of Hair Cycle Camera-type Eye Development Inner Ear Receptor Cell Stereocilium Organization Ciliary Body Morphogenesis Energy Homeostasis Bone Growth Negative Regulation Of Myofibroblast Differentiation
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Asthma ( 31959851) Factor VII activity ( 30642921) Gastroesophageal reflux disease ( 34187846)
Interacting Genes		1 interacting genes: SKIL
Entrez ID		25987
HPRD ID		12152
Ensembl ID		ENSG00000182704
Uniprot IDs		B3KRF9 Q8WUA8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Skeletal Muscle Tissue Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Lymphocyte Homeostasis Response To Antibiotic Lens Fiber Cell Differentiation Positive Regulation Of Axonogenesis Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Leukocyte Homeostasis Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage SMAD Binding Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Blastocyst Formation Positive Regulation Of Apoptotic Signaling Pathway Striated Muscle Tissue Development Extrinsic Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Muscle Structure Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Axonogenesis Muscle Tissue Development Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of BMP Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Acrosomal Vesicle Homeostasis Of Number Of Cells PML Body
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