TIPARP

Gene Name		TCDD-inducible poly(ADP-ribose) polymerase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	NAD+ ADP-ribosyltransferase Activity Enhancer Binding Metal Ion Binding
	Biological Process	Vasculogenesis Kidney Development Protein ADP-ribosylation Nitrogen Compound Metabolic Process Androgen Metabolic Process Estrogen Metabolic Process Female Gonad Development Post-embryonic Development Negative Regulation Of Gene Expression Hemopoiesis Multicellular Organismal Metabolic Process Positive Regulation Of Protein Catabolic Process Platelet-derived Growth Factor Receptor Signaling Pathway Skeletal System Morphogenesis Smooth Muscle Tissue Development Palate Development Face Morphogenesis Cellular Response To Organic Cyclic Compound
Pathways
Drugs
Diseases
GWAS		Ovarian cancer ( 20852632)
Protein-protein Interactions		2 interactors: ATM XRN2
Entrez ID		25976
HPRD ID		18192
Ensembl ID		ENSG00000163659
Uniprot IDs		Q05BQ2 Q7Z3E1
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Catabolic Process Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Aromatic Compound Catabolic Process Pre-B Cell Allelic Exclusion MRNA Metabolic Process Pre-B Cell Differentiation Histone MRNA Catabolic Process Gamete Generation Replicative Senescence Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Immature B Cell Differentiation DNA Damage Induced Protein Phosphorylation Negative Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Sexual Reproduction Lipoprotein Catabolic Process Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Cellular Macromolecule Catabolic Process Positive Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of B Cell Proliferation Mitotic G2 DNA Damage Checkpoint Histone-serine Phosphorylation Cellular Response To Gamma Radiation Histone MRNA Metabolic Process Phosphatidylinositol-3-phosphate Biosynthetic Process Reproduction DNA Metabolic Process V(D)J Recombination Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cellular Response To Heat RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Single Organism Reproductive Process G2 DNA Damage Checkpoint Mitotic Spindle Assembly Checkpoint DNA Catabolic Process, Exonucleolytic Histone Phosphorylation Spindle Assembly Checkpoint Reproductive Process Negative Regulation Of B Cell Activation Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Oocyte Development Oocyte Differentiation Reciprocal Meiotic Recombination Regulation Of Signal Transduction By P53 Class Mediator Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation
Tagcloud ?		1a1 acceleration addresses allergen allergenic allergic basophils beas classroom classrooms coagulation cxcl1 cxcl6 cyp cyp1b1 detoxifying endotoxin eu fel hydrocarbons il6 il8 indoor intensified metabolizing outdoor pm polycyclic xenobiotic