GALNS

Description		galactosamine (N-acetyl)-6-sulfatase
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GO Annotations	Cellular Component	Extracellular Region Lysosome Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	N-acetylgalactosamine-4-sulfatase Activity Arylsulfatase Activity Sulfuric Ester Hydrolase Activity Hydrolase Activity N-acetylgalactosamine-6-sulfatase Activity Metal Ion Binding
	Biological Process
Pathways		Keratan sulfate degradation MPS IV - Morquio syndrome A Neutrophil degranulation
Drugs
Diseases		Mucopolysaccharidosis type IV (MPS4), including: Morquio syndrome A (MPS4A); Morquio syndrome B (MPS4B)
GWAS		Atypical femoral fracture in phosphonate treatment ( 31006051) Hair color ( 26926045)
Interacting Genes		1 interacting genes: MTNR1A
Entrez ID		2588
HPRD ID		08357
Ensembl ID		ENSG00000141012
Uniprot IDs		P34059 Q6YL38 Q96I49
PDB IDs		4FDI 4FDJ
Enriched GO Terms of Interacting Partners?		Melatonin Receptor Activity Mating Behavior Hormone Binding Reproductive Behavior G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Circadian Rhythm Receptor Complex Rhythmic Process Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Activity
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