DCAF12

Gene Name		DDB1 and CUL4 associated factor 12
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Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function
	Biological Process	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: BMPR1B TGFBR1
Entrez ID		25853
HPRD ID		10031
Ensembl ID		ENSG00000198876
Uniprot IDs		Q5T6F0
PDB IDs		3I7P
Enriched GO Terms of Interacting Partners?		Regulation Of Cartilage Development Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Gonad Development Development Of Primary Sexual Characteristics Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Skeletal System Morphogenesis Signal Transduction By Phosphorylation Sex Differentiation Ovarian Cumulus Expansion Negative Regulation Of Chondrocyte Proliferation Camera-type Eye Development Eye Development Pattern Specification Process Reproductive Structure Development Oogenesis Stage Reproductive System Development Antral Ovarian Follicle Growth Skeletal System Development Sensory Organ Development Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Parathyroid Gland Development Positive Regulation Of Cell Death Gamete Generation Negative Regulation Of Cell Proliferation Cell Morphogenesis Involved In Differentiation Developmental Process Involved In Reproduction Endothelial Cell Activation Pathway-restricted SMAD Protein Phosphorylation Sexual Reproduction Positive Regulation Of SMAD Protein Import Into Nucleus Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Regulation Of SMAD Protein Import Into Nucleus Enzyme Linked Receptor Protein Signaling Pathway Germ Cell Migration Pharyngeal System Development Retinal Ganglion Cell Axon Guidance Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Response To Cholesterol Organ Morphogenesis Reproduction Cartilage Condensation Cell Morphogenesis Negative Regulation Of Chondrocyte Differentiation Cardiac Epithelial To Mesenchymal Transition Neuron Differentiation Activin Receptor Signaling Pathway Negative Regulation Of Endothelial Cell Proliferation
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