MTO1

Description		mitochondrial tRNA translation optimization 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Transferase Complex
	Molecular Function	RNA Binding Flavin Adenine Dinucleotide Binding TRNA 5-taurinomethyluridine Synthase Activity
	Biological Process	TRNA Processing TRNA Methylation Mitochondrial TRNA Wobble Uridine Modification
Pathways		tRNA modification in the mitochondrion
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: KDM1A SUV39H1 UBC
Entrez ID		25821
HPRD ID		17611
Ensembl ID		ENSG00000135297
Uniprot IDs		A0A7P0T8Y9 A0A7P0TA27 A0A7P0TAU1 Q9Y2Z2
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3K9 Trimethyltransferase Activity Histone H3K9me2 Methyltransferase Activity RDNA Heterochromatin Formation ENoSc Complex Regulation Of DNA Repair RDNA Heterochromatin Epigenetic Regulation Of Gene Expression Response To Fungicide MRF Binding Histone H3K4 Demethylase Activity Guanine Metabolic Process Protein Demethylase Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Nuclear Lamina Regulation Of DNA Metabolic Process Chromatin Binding Regulation Of Transcription By Glucose Histone H3K9 Methyltransferase Activity Facultative Heterochromatin Formation Epigenetic Programming In The Zygotic Pronuclei Chromatin Silencing Complex Protein Tag Activity Histone H3K9 Demethylase Activity Positive Regulation Of Cell Size Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator DNA Repair Complex Regulation Of Cellular Response To Stress Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator S-adenosylmethionine-dependent Methyltransferase Activity Blastocyst Hatching Chromatin Remodeling Histone H3 Methyltransferase Activity Chromosome Purine Nucleobase Metabolic Process Nuclear Androgen Receptor Binding Positive Regulation Of Neuroblast Proliferation Telomeric DNA Binding Histone Demethylase Activity Histone Methyltransferase Complex Regulation Of Chromatin Organization Cellular Response To Gamma Radiation DNA Repair-dependent Chromatin Remodeling Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Neuron Maturation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Epigenetic Programming Of Gene Expression Determination Of Adult Lifespan
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