SVIP

Description		small VCP interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Secretory Granule Membrane Smooth Endoplasmic Reticulum Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Protein Binding ATPase Binding
	Biological Process	Positive Regulation Of Autophagy Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Protein Lipidation Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of VCP-NPL4-UFD1 AAA ATPase Complex Assembly Negative Regulation Of ERAD Pathway
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Allergic rhinitis ( 25085501) Dialysis-related mortality ( 21546767)
Interacting Genes		3 interacting genes: CDR2L UBXN6 VCP
Entrez ID		258010
HPRD ID
Ensembl ID		ENSG00000198168
Uniprot IDs		Q8NHG7
PDB IDs
Enriched GO Terms of Interacting Partners?		Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Sorting Pathway Endosome To Lysosome Transport ERAD Pathway Flavin Adenine Dinucleotide Catabolic Process Lysosomal Transport VCP-NSFL1C Complex Intracellular Transport Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Macroautophagy Vacuolar Transport Positive Regulation Of Protein K63-linked Deubiquitination Cellular Response To Arsenite Ion Mitotic Spindle Disassembly Positive Regulation Of Oxidative Phosphorylation Golgi To Secretory Granule Transport Response To Endoplasmic Reticulum Stress Cytoplasm Protein Quality Control Endosomal Transport Cellular Localization BAT3 Complex Binding Establishment Of Localization In Cell Positive Regulation Of Protein Deubiquitination Autophagy Positive Regulation Of Mitochondrial Membrane Potential Aggresome Assembly Negative Regulation Of Protein Localization To Chromatin Stress Granule Disassembly Deubiquitinase Activator Activity Protein-DNA Covalent Cross-linking Repair Derlin-1 Retrotranslocation Complex Inclusion Body Assembly VCP-NPL4-UFD1 AAA ATPase Complex Regulation Of Protein Localization To Chromatin K48-linked Polyubiquitin Modification-dependent Protein Binding Ubiquitin-modified Protein Reader Activity Regulation Of Protein Deubiquitination Positive Regulation Of Membrane Potential ATPase Complex Cellular Response To Misfolded Protein Positive Regulation Of Cellular Respiration Response To Misfolded Protein Positive Regulation Of ATP Biosynthetic Process Proteasomal Protein Catabolic Process Retrograde Protein Transport, ER To Cytosol Cellular Response To Arsenic-containing Substance MHC Class I Protein Binding Regulation Of ATP Biosynthetic Process Ubiquitin-specific Protease Binding
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