SVIP

Gene Name		small VCP/p97-interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Hrd1p Ubiquitin Ligase Complex Endoplasmic Reticulum Membrane Plasma Membrane Smooth Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Self-association
	Biological Process	Positive Regulation Of Autophagy Negative Regulation Of Protein Complex Assembly Positive Regulation Of Protein Lipidation Negative Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Dialysis-related mortality ( 21546767)
Protein-protein Interactions		1 interactors: VCP
Entrez ID		258010
HPRD ID
Ensembl ID
Uniprot IDs		Q8NHG7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Retrograde Protein Transport, ER To Cytosol Regulation Of Protein Deubiquitination Protein Hexamerization Aggresome Assembly Translesion Synthesis Postreplication Repair ER-associated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Heat Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Endoplasmic Reticulum Unfolded Protein Response Activation Of Cysteine-type Endopeptidase Activity ER To Golgi Vesicle-mediated Transport Cellular Response To Unfolded Protein Protein N-linked Glycosylation Via Asparagine Zymogen Activation ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Heat DNA Biosynthetic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein N-linked Glycosylation Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Response To Unfolded Protein Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Peptidase Activity Double-strand Break Repair Positive Regulation Of Cellular Protein Catabolic Process Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Complex Assembly Response To Temperature Stimulus Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Protein Catabolic Process Protein Processing Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Homooligomerization Proteasomal Protein Catabolic Process Golgi Vesicle Transport Positive Regulation Of Proteolysis Positive Regulation Of Cellular Component Biogenesis Macromolecule Glycosylation Protein Glycosylation Regulation Of Protein Complex Assembly
Tagcloud ?		affinities arg atpase buster cofactors compete competitors comprised cooperation helix hrd1 interacting lys motif motifs nedd8 nub1l p97 p97n proteasomal referred stronger ultimate valosin vbm vbms vcp vim vital