GABRA6

Gene Name		gamma-aminobutyric acid (GABA) A receptor, alpha 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Chloride Channel Complex Postsynaptic Membrane
	Molecular Function	GABA-A Receptor Activity Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Benzodiazepine Receptor Activity
	Biological Process	Transport Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Synaptic Transmission Ion Transmembrane Transport Transmembrane Transport Chloride Transmembrane Transport
Pathways		GABA receptor activation Ion channel transport GABA A receptor activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ligand-gated ion channel transport Orphan transporters Transmission across Chemical Synapses
Drugs		Lorazepam Ethchlorvynol Temazepam Butabarbital Butalbital Talbutal Pentobarbital Clobazam Meprobamate Alprazolam Secobarbital Metharbital Chlordiazepoxide Thiopental Clorazepate Midazolam Flurazepam Primidone Oxazepam Methylphenobarbital Triazolam Phenobarbital Amobarbital Aprobarbital Butethal Heptabarbital Hexobarbital Barbital Barbituric acid derivative Flunitrazepam Bromazepam Nitrazepam
Diseases
GWAS
Protein-protein Interactions		1 interactors: UBQLN1
Entrez ID		2559
HPRD ID		08841
Ensembl ID		ENSG00000145863
Uniprot IDs		Q16445
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Response To Oxidative Stress Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Endoplasmic Reticulum Stress Regulation Of Protein Ubiquitination Response To Hypoxia
Tagcloud ?		agonistic alpha6 aminobutyric antiepileptic beta3 compromise dravet dysfunctions epilepsy gabaa gabrb2 gabrb3 gabrd gabrg2 gamma2 gastaut gated gating hyperpolarization infantile insufficiencies lennox myoclonic nonsense pathomechanisms pentamers seizures spasms