NPNT

Gene Name		nephronectin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Basement Membrane Smooth Muscle Contractile Fiber Integrin Alpha8-beta1 Complex Extracellular Vesicular Exosome
	Molecular Function	Integrin Binding Calcium Ion Binding
	Biological Process	Ureteric Bud Development Branching Involved In Ureteric Bud Morphogenesis Cell-matrix Adhesion Positive Regulation Of Alkaline Phosphatase Activity Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell-cell Adhesion Mediated By Integrin Establishment Of Protein Localization Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Tumor Necrosis Factor Pilomotor Reflex Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Smooth Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Pulmonary function ( 20010835) Pulmonary function (interaction) ( 23284291)
Protein-protein Interactions		1 interactors: ITGA8
Entrez ID		255743
HPRD ID		14141
Ensembl ID		ENSG00000168743
Uniprot IDs		Q6UXI9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Smooth Muscle Cell Differentiation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mesodermal Cell Differentiation Smooth Muscle Tissue Development Substrate Adhesion-dependent Cell Spreading Smooth Muscle Cell Differentiation Mesoderm Formation Mesoderm Morphogenesis Inner Ear Morphogenesis Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Metanephros Development Memory Ear Morphogenesis Integrin-mediated Signaling Pathway Formation Of Primary Germ Layer Mesoderm Development Cell-matrix Adhesion Regulation Of Cellular Response To Growth Factor Stimulus Inner Ear Development Gastrulation Cell-substrate Adhesion Ear Development Learning Or Memory Cognition Kidney Development Muscle Cell Differentiation Embryonic Organ Morphogenesis Renal System Development Muscle Tissue Development Extracellular Matrix Organization Extracellular Structure Organization Urogenital System Development
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