LPCAT4

Description		lysophosphatidylcholine acyltransferase 4
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity O-acyltransferase Activity Transferase Activity Acyltransferase Activity Lysophosphatidic Acid Acyltransferase Activity 2-acylglycerol-3-phosphate O-acyltransferase Activity 1-alkenylglycerophosphoethanolamine O-acyltransferase Activity 1-acylglycerophosphocholine O-acyltransferase Activity 1-alkylglycerophosphocholine O-acetyltransferase Activity Lysophospholipid Acyltransferase Activity 1-acylglycerophosphoethanolamine O-acyltransferase Activity 1-acylglycerophosphoserine O-acyltransferase Activity
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PG Synthesis of PA
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
Interacting Genes		3 interacting genes: CFTR ERBB2 OGT
Entrez ID		254531
HPRD ID		08315
Ensembl ID		ENSG00000176454
Uniprot IDs		Q643R3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Localization Regulation Of Protein Localization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Early Endosome Positive Regulation Of Cell Communication Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Positive Regulation Of Signaling Endosome Membrane Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Establishment Of Protein Localization Membrane Hyperpolarization Basolateral Plasma Membrane Negative Regulation Of Immature T Cell Proliferation In Thymus RNA Polymerase I Core Binding Negative Regulation Of Immature T Cell Proliferation ErbB-3 Class Receptor Binding ERBB3:ERBB2 Complex Regulation Of Small GTPase Mediated Signal Transduction Immature T Cell Proliferation In Thymus ERBB2-ERBB4 Signaling Pathway Positive Regulation Of Translation Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Apical Plasma Membrane ERBB2-EGFR Signaling Pathway Amelogenesis ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Regulation Of Transcription By Glucose ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Negative Regulation Of T Cell Differentiation In Thymus Regulation Of Translation NSL Complex
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