LCLAT1

Description		lysocardiolipin acyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System Membrane
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding O-acyltransferase Activity Transferase Activity Acyltransferase Activity
	Biological Process	Lipid Metabolic Process Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process Cardiolipin Acyl-chain Remodeling Phosphatidylinositol Acyl-chain Remodeling
Pathways		Acyl chain remodeling of CL Synthesis of PA
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		3 interacting genes: GOPC LNX1 PICK1
Entrez ID		253558
HPRD ID		17458
Ensembl ID		ENSG00000172954
Uniprot IDs		B4DM26 B4DYR5 Q6UWP7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Anion Channel Activity Postsynaptic Density Membrane Curvature Sensor Activity Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Identical Protein Binding Negative Regulation Of Actin Nucleation Localization Within Membrane Neuronal Ion Channel Clustering Arp2/3 Complex Binding Dendritic Spine Maintenance Long-term Synaptic Depression Negative Regulation Of Protein Localization To Cell Surface Regulation Of Monoatomic Anion Transport Molecular Sequestering Activity Golgi-associated Vesicle Membrane Trans-Golgi Network Transport Vesicle Apical Protein Localization Synapse Maturation Positive Regulation Of Receptor Internalization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Monoamine Transport Negative Regulation Of Transporter Activity Dendritic Spine Organization Regulation Of Actin Nucleation Negative Regulation Of Synaptic Transmission Regulation Of Protein Localization To Cell Surface Cellular Response To Glucose Starvation Receptor Clustering Neuron Projection Organization Protein Kinase C Binding Postsynapse Organization Synapse Regulation Of Protein Localization Hippocampal Mossy Fiber To CA3 Synapse Positive Regulation Of Receptor-mediated Endocytosis
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