FUT1

Description		fucosyltransferase 1 (H blood group)
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Golgi Apparatus Plasma Membrane Membrane Golgi Cisterna Membrane
	Molecular Function	Galactoside 2-alpha-L-fucosyltransferase Activity Fucosyltransferase Activity Transferase Activity Glycosyltransferase Activity Alpha-(1,2)-fucosyltransferase Activity
	Biological Process	Regulation Of Endothelial Cell Proliferation Positive Regulation Of Cell-matrix Adhesion Carbohydrate Metabolic Process Protein Glycosylation Lipid Metabolic Process Glycosphingolipid Biosynthetic Process Oligosaccharide Biosynthetic Process Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Triglyceride Catabolic Process Response To Activity Olfactory Bulb Development Regulation Of Cell Adhesion Endoplasmic Reticulum Unfolded Protein Response Response To Nutrient Levels Fucosylation L-fucose Catabolic Process Cellular Response To Glucose Stimulus Cellular Response To Glucagon Stimulus Cellular Response To Low-density Lipoprotein Particle Stimulus Cellular Response To Xenobiotic Stimulus Endothelial Cell Apoptotic Process Positive Regulation Of Sprouting Angiogenesis Response To Methionine Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		ABO blood group biosynthesis Glycosphingolipid biosynthesis
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30643258) Bipolar disorder ( 21926972) Cooked vegetable consumption ( 32066663) Dietary macronutrient intake ( 23372041) Elevated serum carcinoembryonic antigen levels ( 24941225) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Intake of total sugars ( 31005972) Meat-related diet ( 32066663) Non-oily fish consumption ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Processed meat consumption ( 32066663) Retinal vascular caliber ( 21060863) Serum alkaline phosphatase levels ( 33339817) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)
Novel Interacting Genes		1 novel interacting genes: VPS11
Interacting Genes
Entrez ID		2523
HPRD ID		07186
Ensembl ID		ENSG00000174951
Uniprot IDs		P19526 Q6IZA2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Vesicle Tethering Complex Positive Regulation Of Early Endosome To Late Endosome Transport CORVET Complex Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway HOPS Complex Regulation Of Early Endosome To Late Endosome Transport Syntaxin Binding Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Vesicle Docking Involved In Exocytosis Autophagosome Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Clathrin-coated Vesicle Regulation Of Protein Targeting To Mitochondrion Endosome Organization Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Endosome To Lysosome Transport Endocytic Vesicle Regulation Of Intracellular Estrogen Receptor Signaling Pathway Vesicle Docking Positive Regulation Of Protein Targeting To Mitochondrion Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Organelle Membrane Fusion Lysosomal Transport Organelle Fusion Positive Regulation Of Intracellular Transport Late Endosome Membrane Late Endosome Membrane Fusion Vacuolar Transport Vacuole Organization Protein-macromolecule Adaptor Activity Positive Regulation Of Protein Catabolic Process Protein Domain Specific Binding Regulation Of Organelle Assembly Regulation Of Intracellular Transport
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