ALPI

Description		alkaline phosphatase, intestinal
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Side Of Membrane
	Molecular Function	Magnesium Ion Binding Protease Binding Alkaline Phosphatase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Phosphatase Activity Metal Ion Binding
	Biological Process	Dephosphorylation
Pathways		Synthesis of PA Post-translational modification: synthesis of GPI-anchored proteins Digestion
Drugs		Terpinen-4-ol
Diseases
GWAS		Hepcidin/ferritin ratio ( 27846281) Refractive error ( 32231278)
Novel Interacting Genes		1 novel interacting genes: AGAP1
Interacting Genes		8 interacting genes: BICD1 HSPB1 IRF5 KRTAP10-3 KRTAP10-8 KRTAP10-9 NOD2 NOTCH2NLA
Entrez ID		248
HPRD ID		01376
Ensembl ID		ENSG00000163295
Uniprot IDs		P09923
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Peptidoglycan Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Cellular Response To Muramyl Dipeptide Response To Peptidoglycan Keratin Filament Protein Kinase Binding Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Muramyl Dipeptide Intermediate Filament Positive Regulation Of Notch Signaling Pathway Negative Regulation Of Protein Kinase C Signaling Positive Regulation Of Interleukin-1 Beta Production Detection Of Muramyl Dipeptide Muramyl Dipeptide Binding Positive Regulation Of Interleukin-1 Production Negative Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytokine Production Involved In Immune Response Detection Of Peptidoglycan Regulation Of Notch Signaling Pathway Ubiquitin Binding Regulation Of Interleukin-1 Beta Production Cytoplasmic Pattern Recognition Receptor Signaling Pathway Proteinase Activated Receptor Binding Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Positive Regulation Of Tumor Necrosis Factor Production Protein Kinase C Inhibitor Activity Positive Regulation Of Cytokine Production Regulation Of Cytokine Production Involved In Immune Response Minus-end-directed Organelle Transport Along Microtubule Regulation Of Protein Kinase C Signaling Anion Binding Postsynaptic Endosome Constitutive Secretory Pathway Transport Along Microtubule Positive Regulation Of Protein Localization To Centrosome Secretory Vesicle Virion Assembly Cytoskeleton-dependent Intracellular Transport Regulation Of Tumor Necrosis Factor Production Anterograde Axonal Protein Transport Innate Immune Response-activating Signaling Pathway Regulation Of Production Of Molecular Mediator Of Immune Response Pattern Recognition Receptor Signaling Pathway Cellular Response To Molecule Of Bacterial Origin Positive Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Intestinal Stem Cell Homeostasis Protein Linear Polyubiquitination Carbohydrate Derivative Binding
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