FLRT3

Description		fibronectin leucine rich transmembrane protein 3
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Membrane Cell Junction Axon Extracellular Matrix Growth Cone Membrane Presynaptic Membrane Cell Projection Axon Terminus Axonal Growth Cone Synapse Postsynaptic Membrane Anchoring Junction Synaptic Membrane Glutamatergic Synapse
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Protein-macromolecule Adaptor Activity Protein Homodimerization Activity Chemorepellent Activity
	Biological Process	Proepicardium Cell Migration Involved In Pericardium Morphogenesis Cell Adhesion Axon Guidance Synapse Assembly Heart Development Fibroblast Growth Factor Receptor Signaling Pathway Neuron Projection Development Embryonic Morphogenesis Response To Axon Injury Negative Chemotaxis Positive Regulation Of Synapse Assembly Head Development Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Synaptic Membrane Adhesion Neuron Projection Extension
Pathways		Signaling by ROBO receptors Downstream signaling of activated FGFR1
Drugs
Diseases
GWAS		Bipolar disorder ( 33169155) Blood protein levels ( 30072576) Mood disorder in prion disease ( 25897833)
Novel Interacting Genes		1 novel interacting genes: IRF4
Interacting Genes		2 interacting genes: FGFR1 UNC5B
Entrez ID		23767
HPRD ID		05313
Ensembl ID		ENSG00000125848
Uniprot IDs		Q9NZU0
PDB IDs		5CMN 5CMP 6JBU
Enriched GO Terms of Interacting Partners?		Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Vitamin D3 Metabolic Process Lung-associated Mesenchyme Development Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Branching Involved In Salivary Gland Morphogenesis Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Positive Regulation Of Mitotic Cell Cycle DNA Replication Outer Ear Morphogenesis Positive Regulation Of Lipase Activity Receptor-receptor Interaction Ventricular Zone Neuroblast Division Regulation Of Mesodermal Cell Differentiation Mesenchymal-epithelial Cell Signaling Regulation Of Mitotic Cell Cycle DNA Replication Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Cementum Mineralization Diphosphate Metabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Fibroblast Growth Factor Receptor Activity Regulation Of Branching Involved In Salivary Gland Morphogenesis By Mesenchymal-epithelial Signaling Auditory Receptor Cell Development Orbitofrontal Cortex Development Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Fibroblast Growth Factor Production Angiogenesis Paraxial Mesoderm Development Response To Sodium Phosphate Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of Phospholipase Activity Regulation Of Phosphate Transport Forebrain Neuroblast Division Regulation Of Lateral Mesodermal Cell Fate Specification Forebrain Ventricular Zone Progenitor Cell Division Positive Regulation Of Parathyroid Hormone Secretion Netrin-activated Signaling Pathway Anterior/posterior Axon Guidance Netrin Receptor Activity Salivary Gland Morphogenesis Branching Involved In Salivary Gland Morphogenesis Regulation Of Nuclear Cell Cycle DNA Replication Neuron Projection Development Vitamin D Metabolic Process Inner Ear Receptor Cell Development Ear Development T-helper 17 Cell Lineage Commitment Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of DNA-templated DNA Replication Positive Regulation Of Interleukin-13 Production Regulation Of Postsynaptic Density Assembly
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