OSBP2

Description		oxysterol binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle Perinuclear Endoplasmic Reticulum Apical Dendrite
	Molecular Function	Protein Binding Lipid Binding Cholesterol Binding Sterol Binding
	Biological Process	Lipid Transport Spermatogenesis Spermatid Development Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine) ( 23648065) Estimated glomerular filtration rate change in renal transplantation (donor effect) ( 30920136) Red cell distribution width ( 32888494) Refractive error ( 32231278) Response to ketamine in bipolar disorder or major depression (antidepressant effects) ( 30552317) Takayasu arteritis ( 33308445)
Interacting Genes		6 interacting genes: DLG3 GOPC LNX1 PICK1 TNNT1 VIM
Entrez ID		23762
HPRD ID		09471
Ensembl ID		ENSG00000184792
Uniprot IDs		Q969R2
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuron Projection Receptor Clustering Slow-twitch Skeletal Muscle Fiber Contraction Glial Cell Development Negative Regulation Of Anion Channel Activity Localization Within Membrane Troponin T Binding Identical Protein Binding Membrane Curvature Sensor Activity Keratin Filament Binding Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Troponin Complex Transition Between Fast And Slow Fiber Lens Fiber Cell Development Protein Domain Specific Binding Negative Regulation Of Actin Nucleation Regulation Of Skeletal Muscle Adaptation Cellular Response To Muramyl Dipeptide Bergmann Glial Cell Differentiation Postsynaptic Density Neuronal Ion Channel Clustering Dendritic Spine Maintenance
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