DDAH1

Gene Name		dimethylarginine dimethylaminohydrolase 1
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Extracellular Vesicular Exosome
	Molecular Function	Catalytic Activity Dimethylargininase Activity Amino Acid Binding Metal Ion Binding
	Biological Process	Citrulline Metabolic Process Regulation Of Systemic Arterial Blood Pressure Arginine Catabolic Process Nitric Oxide Mediated Signal Transduction Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Angiogenesis
Pathways
Drugs		L-Citrulline
Diseases
GWAS		Multiple sclerosis ( 21833088)
Protein-protein Interactions		1 interactors: CALM1
Entrez ID		23576
HPRD ID		09203
Ensembl ID		ENSG00000153904
Uniprot IDs		B1AKK2 B4DGT0 B4DYP1 B4E3V1 O94760
PDB IDs		2JAI 2JAJ 3I2E 3I4A 3P8E 3P8P
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine Positive Regulation Of Adenylate Cyclase Activity Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Nitric-oxide Synthase Activity Response To Mineralocorticoid Substantia Nigra Development Positive Regulation Of Oxidoreductase Activity Negative Regulation Of Transporter Activity Negative Regulation Of Calcium Ion Transport Positive Regulation Of Lyase Activity Positive Regulation Of Dephosphorylation Negative Regulation Of Ion Transmembrane Transport Response To Amine Inositol Phosphate Metabolic Process Activation Of Phospholipase C Activity Positive Regulation Of Ion Transmembrane Transporter Activity
Tagcloud ?		abeta ad adma appsw arginine asymmetric attenuating caenorhabditis cardiovascular cl2006 collectively contributes dimethylaminohydrolase dimethylarginine elegans exacerbated failed growing methyltransferase nitric overexpressing oxidative paralysis secretion sh swedish sy5y synthase worms