SEZ6L

Description		seizure related 6 homolog like
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Neuronal Cell Body
	Molecular Function	Protein Binding
	Biological Process	Adult Locomotory Behavior Cerebellar Purkinje Cell Layer Development Synapse Maturation
Pathways
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Copper levels ( 26025379) Insulin resistance/response ( 21901158) Vascular brain injury ( 25188341)
Interacting Genes		5 interacting genes: APP GPRASP2 RSPH1 UBQLN1 UBQLN2
Entrez ID		23544
HPRD ID		08449
Ensembl ID		ENSG00000100095
Uniprot IDs		B7ZLJ8 Q9BYH1
PDB IDs		2YRA
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of ERAD Pathway Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Regulation Of Proteolysis Regulation Of Protein Catabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway G Protein-coupled Receptor Binding Regulation Of Cellular Response To Stress Regulation Of Receptor Internalization Autophagosome Autophagosome Assembly ERAD Pathway Negative Regulation Of Store-operated Calcium Channel Activity Positive Regulation Of Catabolic Process Autophagosome Organization Positive Regulation Of Proteasomal Protein Catabolic Process Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Receptor-mediated Endocytosis Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Radial Spoke Head 1 Radial Spoke Head 3 Positive Regulation Of Protein Metabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Cytoplasmic Vesicle
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