SEC14L2

Description		SEC14 like lipid binding 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Phospholipid Binding Lipid Binding Vitamin E Binding
	Biological Process	Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of DNA-templated Transcription
Pathways
Drugs		Vitamin E alpha-Tocopherol succinate D-alpha-Tocopherol acetate
Diseases
GWAS		Breast size ( 22747683) Plateletcrit ( 27863252)
Novel Interacting Genes		1 novel interacting genes: CD28
Interacting Genes		1 interacting genes: PIK3CG
Entrez ID		23541
HPRD ID		06344
Ensembl ID		ENSG00000100003
Uniprot IDs		B7Z3Z8 O76054
PDB IDs		1O6U 1OLM 4OMJ 4OMK
Enriched GO Terms of Interacting Partners?		Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Lymphocyte Proliferation T Cell Proliferation Mononuclear Cell Proliferation Leukocyte Proliferation Positive Regulation Of Inflammatory Response Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction T Cell Activation Natural Killer Cell Chemotaxis Positive Regulation Of Cytokine Production Protein Complex Involved In Cell Adhesion Leukocyte Activation Regulation Of Inflammatory Response Regulatory T Cell Differentiation Lymphocyte Activation CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Defense Response 1-phosphatidylinositol-3-kinase Activity Negative Regulation Of Cardiac Muscle Contraction Phosphatidylinositol 3-kinase Complex, Class IB Negative Regulation Of Striated Muscle Contraction Respiratory Burst Involved In Defense Response Phosphatidylinositol 3-kinase Complex Negative Regulation Of Triglyceride Catabolic Process 1-phosphatidylinositol-4-phosphate 3-kinase Activity Negative Regulation Of Fibroblast Apoptotic Process Phosphatidylinositol 3-kinase Complex, Class IA 1-phosphatidylinositol-4,5-bisphosphate 3-kinase Activity Neutrophil Extravasation Positive Regulation Of Isotype Switching To IgG Isotypes Positive Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Regulation Of Defense Response Regulation Of Cell Adhesion Thymic T Cell Selection Intracellular Signaling Cassette Cell Activation Alpha-beta T Cell Proliferation Negative Regulation Of Apoptotic Process Negative Thymic T Cell Selection Positive Regulation Of Inflammatory Response To Antigenic Stimulus Negative T Cell Selection Regulation Of Isotype Switching To IgG Isotypes Cell Population Proliferation Hepatocyte Apoptotic Process Regulation Of Fibroblast Apoptotic Process Secretory Granule Localization Positive Regulation Of Rac Protein Signal Transduction
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