ACAP2

Description		ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
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GO Annotations	Cellular Component	Ruffle Cytoplasm Endosome Plasma Membrane Endosome Membrane Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Actin Filament-based Process Endocytic Recycling Cellular Response To Nerve Growth Factor Stimulus
Pathways
Drugs
Diseases
GWAS		Body mass index ( 25673413) Height ( 31562340) Mean platelet volume ( 32888494)
Interacting Genes		1 interacting genes: HSPB1
Entrez ID		23527
HPRD ID		09681
Ensembl ID		ENSG00000114331
Uniprot IDs		Q15057
PDB IDs		6IF3
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Kinase C Signaling Regulation Of Protein Kinase C Signaling Positive Regulation Of Endothelial Cell Chemotaxis Protein Transport Along Microtubule Anterograde Axonal Protein Transport Protein Kinase C Inhibitor Activity Contractile Muscle Fiber Cellular Response To Vascular Endothelial Growth Factor Stimulus Protein Refolding Protein Localization To Synapse Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Migration Protein Folding Chaperone Protein Kinase C Binding Platelet Aggregation Axon Cytoplasm Positive Regulation Of Interleukin-1 Beta Production Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Axonal Transport Anterograde Axonal Transport Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Cornified Envelope Proteasome Complex Homotypic Cell-cell Adhesion Positive Regulation Of Interleukin-1 Production Response To Unfolded Protein Protein Localization To Cell Junction Response To Heat Axo-dendritic Transport Regulation Of Translational Initiation Regulation Of Interleukin-1 Production Unfolded Protein Binding Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Positive Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Endothelial Cell Migration Ubiquitin Binding Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Interleukin-1 Beta Production Z Disc Positive Regulation Of Chemotaxis Response To Temperature Stimulus Positive Regulation Of Vasculature Development Positive Regulation Of Angiogenesis Regulation Of Tumor Necrosis Factor Production Transport Along Microtubule Regulation Of Endothelial Cell Migration RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Cytoskeleton-dependent Intracellular Transport
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