ABCA5

Description		ATP binding cassette subfamily A member 5
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Lysosomal Membrane Endosome Late Endosome Golgi Apparatus Plasma Membrane Membrane Late Endosome Membrane
	Molecular Function	Nucleotide Binding Lipid Transporter Activity ATP Binding ATP Hydrolysis Activity ATPase-coupled Transmembrane Transporter Activity ABC-type Transporter Activity
	Biological Process	Lipid Transport Cholesterol Metabolic Process Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Cholesterol Efflux Cholesterol Efflux High-density Lipoprotein Particle Remodeling Cholesterol Homeostasis Reverse Cholesterol Transport Transmembrane Transport Positive Regulation Of Reverse Cholesterol Transport
Pathways		ABC transporters in lipid homeostasis
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Iron status biomarkers (iron levels) ( 33536631) Metabolite levels ( 23823483) Normal facial asymmetry (deformation magnitude) ( 30631343)
Interacting Genes		2 interacting genes: CYP2E1 NR4A1
Entrez ID		23461
HPRD ID		09789
Ensembl ID		ENSG00000154265
Uniprot IDs		Q8WWZ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Carbon Tetrachloride Metabolic Process Halogenated Hydrocarbon Metabolic Process 4-nitrophenol Metabolic Process 4-nitrophenol 2-monooxygenase Activity Benzene Metabolic Process Lipid Hydroxylation Long-chain Fatty Acid Omega-1 Hydroxylase Activity Monoterpenoid Metabolic Process Non-canonical Inflammasome Complex Assembly Detection Of Lipopolysaccharide Cellular Response To Corticotropin-releasing Hormone Stimulus Arachidonate Epoxygenase Activity Epoxygenase P450 Pathway Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Detection Of Molecule Of Bacterial Origin Nuclear Glucocorticoid Receptor Binding Regulation Of Type B Pancreatic Cell Proliferation Endothelial Cell Chemotaxis Benzene-containing Compound Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Oxygen Binding Cell Migration Involved In Sprouting Angiogenesis Detection Of Biotic Stimulus Cellular Response To Vascular Endothelial Growth Factor Stimulus Cellular Response To Fibroblast Growth Factor Stimulus Long-chain Fatty Acid Biosynthetic Process Lipopolysaccharide Binding Blood Vessel Endothelial Cell Migration Hsp90 Protein Binding Response To Fibroblast Growth Factor Arachidonate Metabolic Process Hsp70 Protein Binding Response To External Biotic Stimulus Nuclear Receptor Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Skeletal Muscle Cell Differentiation Monooxygenase Activity Macrophage Activation Mitochondrion Phenol-containing Compound Metabolic Process Endothelial Cell Migration
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