SLC35A3

Description		solute carrier family 35 member A3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	UDP-galactose Transmembrane Transporter Activity UDP-N-acetylglucosamine Transmembrane Transporter Activity Protein Binding Pyrimidine Nucleotide-sugar Transmembrane Transporter Activity Antiporter Activity
	Biological Process	UDP-N-acetylglucosamine Metabolic Process Transmembrane Transport UDP-galactose Transmembrane Transport Pyrimidine Nucleotide-sugar Transmembrane Transport UDP-N-acetylglucosamine Transmembrane Transport
Pathways		Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS) Transport of nucleotide sugars
Drugs
Diseases
GWAS		Incident chronic kidney disease ( 30955190)
Interacting Genes		2 interacting genes: CRADD TP63
Entrez ID		23443
HPRD ID		10413
Ensembl ID		ENSG00000117620
Uniprot IDs		A0A1W2PQL8 A0A1W2PR66 A0A1W2PRT7 A0A1W2PSD1 Q9Y2D2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Apoptotic Signaling Pathway Female Genitalia Morphogenesis Positive Regulation Of Somatic Stem Cell Population Maintenance Signal Transduction By P53 Class Mediator Cloacal Septation Ectoderm And Mesoderm Interaction Epidermal Cell Division Apoptotic Signaling Pathway Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Negative Regulation Of Mesoderm Development Regulation Of Epidermal Cell Division Death Domain Binding Endopeptidase Complex Prostatic Bud Formation Regulation Of Apoptotic Signaling Pathway Morphogenesis Of A Polarized Epithelium Regulation Of Mesoderm Development Positive Regulation Of Programmed Cell Death Lateral Sprouting From An Epithelium Positive Regulation Of Apoptotic Process Epithelial Cell Differentiation Involved In Prostate Gland Development Negative Regulation Of Keratinocyte Differentiation Positive Regulation Of Fibroblast Apoptotic Process Genitalia Morphogenesis MDM2/MDM4 Family Protein Binding Regulation Of Somatic Stem Cell Population Maintenance Skin Morphogenesis Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Epidermal Cell Differentiation Morphogenesis Of An Epithelial Fold Prostate Gland Development Positive Regulation Of Keratinocyte Proliferation Sympathetic Nervous System Development Cranial Skeletal System Development DNA Damage Response Post-anal Tail Morphogenesis Glandular Epithelial Cell Differentiation Cell Death Regulation Of Fibroblast Apoptotic Process Establishment Of Planar Polarity Apoptotic Process Prostate Gland Epithelium Morphogenesis Programmed Cell Death WW Domain Binding Polarized Epithelial Cell Differentiation Animal Organ Formation Negative Regulation Of Cellular Senescence Morphogenesis Of Embryonic Epithelium Embryonic Hindlimb Morphogenesis Keratinocyte Proliferation
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