SIRT4

Gene Name		sirtuin 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	NAD+ ADP-ribosyltransferase Activity Protein Binding Zinc Ion Binding NAD-dependent Protein Deacetylase Activity NAD+ Binding
	Biological Process	Chromatin Silencing Protein ADP-ribosylation Glutamine Metabolic Process Cellular Response To DNA Damage Stimulus Peptidyl-lysine Deacetylation Negative Regulation Of Fatty Acid Oxidation Negative Regulation Of Insulin Secretion Positive Regulation Of Lipid Biosynthetic Process Tricarboxylic Acid Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: SKP2
Entrez ID		23409
HPRD ID		06837
Ensembl ID		ENSG00000089163
Uniprot IDs		Q9Y6E7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Cell-matrix Adhesion Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Smooth Muscle Cell Proliferation Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Smooth Muscle Cell Proliferation G2/M Transition Of Mitotic Cell Cycle G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination Cellular Response To Extracellular Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition
Tagcloud ?		anaplerotic aspartate catabolism conversions converted converts dehydrogenase glutamic glutamine glutaminolysis hallmarks intermediates ketoglutarate maintain malate nadp nadph oncogenes oxaloacetate pools proliferating pyruvate redox stimulates supports suppresses suppressors tca utilize