DOCK9

Gene Name		dedicator of cytokinesis 9
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Gene Ontology Annotations	Cellular Component	Cytosol Endomembrane System Membrane
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rho GTPase Binding
	Biological Process	Small GTPase Mediated Signal Transduction Blood Coagulation Biological_process Positive Regulation Of Rho GTPase Activity
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: CDC42 LNX1
Entrez ID		23348
HPRD ID		09542
Ensembl ID		ENSG00000088387
Uniprot IDs		A6H8Z6 B3KXE2 B9EG73 Q9BZ29
PDB IDs		1WG7 2WM9 2WMN 2WMO
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Hair Follicle Cell Proliferation Actin Filament Branching Submandibular Salivary Gland Formation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Establishment Of Golgi Localization Positive Regulation Of Metalloenzyme Activity Neuron Fate Determination Epithelial-mesenchymal Cell Signaling Regulation Of Protein Heterodimerization Activity Keratinocyte Development Regulation Of Synapse Structural Plasticity Positive Regulation Of Pseudopodium Assembly Nuclear Migration Cardiac Conduction System Development Golgi Localization Filopodium Assembly Hair Follicle Placode Formation Macrophage Differentiation Regulation Of Attachment Of Spindle Microtubules To Kinetochore Dendritic Cell Migration Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Of Nucleus Localization Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Substrate Adhesion-dependent Cell Spreading Hair Follicle Morphogenesis Epithelial Cell-cell Adhesion Substantia Nigra Development Positive Regulation Of Cytokinesis Epidermis Morphogenesis Keratinization Salivary Gland Morphogenesis Nucleus Localization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Salivary Gland Development Regulation Of Filopodium Assembly Negative Regulation Of ERBB Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity Cell Fate Determination Skin Morphogenesis Neural Nucleus Development Organelle Transport Along Microtubule Sprouting Angiogenesis Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Cytokinesis Regulation Of Lipid Kinase Activity Exocrine System Development Positive Regulation Of Neuron Apoptotic Process Heart Contraction
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