AFF2

Description		ALF transcription elongation factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Speck Super Elongation Complex
	Molecular Function	G-quadruplex RNA Binding RNA Binding
	Biological Process	MRNA Processing Brain Development Learning Or Memory RNA Splicing Regulation Of Gene Expression Negative Regulation Of Gene Expression Nuclear Speck Organization Regulation Of RNA Splicing
Pathways
Drugs
Diseases		Non-syndromic X-linked mental retardation
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494)
Interacting Genes		2 interacting genes: KPNA4 RNF10
Entrez ID		2334
HPRD ID		02397
Ensembl ID		ENSG00000155966
Uniprot IDs		P51816
PDB IDs
Enriched GO Terms of Interacting Partners?		Dopamine Secretion Catecholamine Secretion NLS-dependent Protein Nuclear Import Complex Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Postsynapse To Nucleus Signaling Pathway Negative Regulation Of Schwann Cell Proliferation Extrinsic Component Of Postsynaptic Density Membrane Positive Regulation Of Hippo Signaling Nuclear Import Signal Receptor Activity Nuclear Localization Sequence Binding Dopamine Transport Positive Regulation Of Myelination Negative Regulation Of Glial Cell Proliferation NLS-bearing Protein Import Into Nucleus Monoamine Transport Regulation Of Hippo Signaling Regulation Of Glial Cell Proliferation Negative Regulation Of Gliogenesis Regulation Of Myelination Male Germ Cell Nucleus Postsynaptic Signal Transduction Protein Monoubiquitination Protein Autoubiquitination
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