ADGRL3

Description		adhesion G protein-coupled receptor L3
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GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Membrane Axon Cell Projection Synapse Postsynaptic Membrane Anchoring Junction Glutamatergic Synapse
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding Carbohydrate Binding Metal Ion Binding Cell Adhesion Mediator Activity Molecular Condensate Scaffold Activity
	Biological Process	Neuron Migration Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Synapse Assembly Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Rho-activating G Protein-coupled Receptor Signaling Pathway Excitatory Synapse Assembly
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Age at first sexual intercourse ( 34211149) Chronic kidney disease ( 30226566) Coronary artery disease ( 30402224) Ischemic stroke ( 29930801) Myocardial infarction ( 30226566)
Interacting Genes		1 interacting genes: CRK
Entrez ID		23284
HPRD ID		10055
Ensembl ID		ENSG00000150471
Uniprot IDs		A0A804HKL8 B7Z2G2 E7ESV6 E7EUP0 E7EUW2 E7EVD6 Q9HAR2
PDB IDs		5CMN 6VHH 7SF7 8DJG
Enriched GO Terms of Interacting Partners?		Helper T Cell Diapedesis Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin Cerebellar Neuron Development Response To Hepatocyte Growth Factor Cellular Response To Nitric Oxide Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Diapedesis Positive Regulation Of Receptor Clustering Regulation Of Receptor Clustering Insulin-like Growth Factor Receptor Binding Cellular Response To Insulin-like Growth Factor Stimulus Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Reelin-mediated Signaling Pathway Cellular Response To Reactive Nitrogen Species Response To Endothelin Response To Yeast Cellular Response To Endothelin Postsynaptic Specialization Assembly Positive Regulation Of Rac Protein Signal Transduction Response To Nitric Oxide Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Postsynaptic Specialization Organization Ephrin Receptor Binding Signaling Receptor Complex Adaptor Activity Regulation Of Rac Protein Signal Transduction Response To Nerve Growth Factor Dendrite Development SH2 Domain Binding Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Central Nervous System Neuron Development Protein Tyrosine Kinase Binding Positive Regulation Of Smooth Muscle Cell Migration T Cell Migration Cellular Response To Nerve Growth Factor Stimulus Phosphotyrosine Residue Binding Regulation Of T Cell Migration Regulation Of Cell Adhesion Mediated By Integrin Ephrin Receptor Signaling Pathway Lymphocyte Migration Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Smooth Muscle Cell Migration Regulation Of Substrate Adhesion-dependent Cell Spreading Cytoskeletal Protein Binding Regulation Of Lymphocyte Migration Hippocampus Development Negative Regulation Of Wound Healing Response To Fungus Cellular Response To Transforming Growth Factor Beta Stimulus
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