DENND5A

Description		DENN domain containing 5A
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Retromer Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding
	Biological Process	Negative Regulation Of Neuron Projection Development Retrograde Transport, Endosome To Golgi
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)
Interacting Genes		4 interacting genes: AR CSNK2B GOLGA6L9 PRKCZ
Entrez ID		23258
HPRD ID		11475
Ensembl ID		ENSG00000184014
Uniprot IDs		A0A7P0Z4N9 Q6IQ26
PDB IDs
Enriched GO Terms of Interacting Partners?		Lateral Sprouting Involved In Mammary Gland Duct Morphogenesis Prostate Induction Androgen Binding Male Genitalia Morphogenesis POU Domain Binding Positive Regulation Of Intracellular Signal Transduction RNA Polymerase II General Transcription Initiation Factor Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Tertiary Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Cellular Response To Testosterone Stimulus Regulation Of Prostatic Bud Formation Male Somatic Sex Determination Positive Regulation Of Integrin Biosynthetic Process Hormone-mediated Signaling Pathway Positive Regulation Of Activin Receptor Signaling Pathway Protein Kinase CK2 Complex Negative Regulation Of Viral Life Cycle Symbiont-mediated Disruption Of Host Cell PML Body Release From Viral Latency Myelin Sheath Abaxonal Region Apical Cortex Positive Regulation Of T-helper 2 Cell Differentiation PAR Polarity Complex Axon Hillock Genitalia Morphogenesis Developmental Growth Positive Regulation Of Signal Transduction Signaling Receptor Binding Lateral Sprouting From An Epithelium Male Sex Determination Leydig Cell Differentiation Morphogenesis Of An Epithelium Estrogen Response Element Binding Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Prostate Gland Growth Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Tissue Morphogenesis Epithelial Cell Differentiation Involved In Prostate Gland Development Cellular Response To Hormone Stimulus Phosphorylation Protein Phosphorylation Protein Serine/threonine Kinase Activity Endothelial Tube Morphogenesis Adiponectin-activated Signaling Pathway Positive Regulation Of T-helper 2 Cell Cytokine Production Insulin Receptor Substrate Binding Positive Regulation Of Interleukin-5 Production Morphogenesis Of An Epithelial Fold
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