BOP1

Description		BOP1 ribosomal biogenesis factor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Preribosome, Large Subunit Precursor PeBoW Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	Ribosomal Large Subunit Assembly Cleavage In ITS2 Between 5.8S RRNA And LSU-rRNA Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Cell Population Proliferation Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Regulation Of Cell Cycle Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Type 2 diabetes ( 30297969)
Interacting Genes		2 interacting genes: KLF10 PES1
Entrez ID		23246
HPRD ID		16558
Ensembl ID		ENSG00000261236
Uniprot IDs		Q14137
PDB IDs		8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY
Enriched GO Terms of Interacting Partners?		Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) PeBoW Complex Core Promoter Sequence-specific DNA Binding Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA Preribosome, Large Subunit Precursor
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