SULF1

Gene Name		sulfatase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Golgi Apparatus Golgi Stack Plasma Membrane Cell Surface Membrane Raft
	Molecular Function	Arylsulfatase Activity Calcium Ion Binding N-acetylglucosamine-6-sulfatase Activity
	Biological Process	Kidney Development Negative Regulation Of Endothelial Cell Proliferation Chondrocyte Development Glomerular Filtration Apoptotic Process Positive Regulation Vascular Endothelial Growth Factor Production Esophagus Smooth Muscle Contraction Negative Regulation Of Angiogenesis Positive Regulation Of Wnt Signaling Pathway Heparan Sulfate Proteoglycan Metabolic Process Negative Regulation Of Cell Migration Positive Regulation Of BMP Signaling Pathway Glomerular Basement Membrane Development Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Embryonic Skeletal System Development Cartilage Development Bone Development Innervation Negative Regulation Of Prostatic Bud Formation
Pathways
Drugs
Diseases
GWAS		Dupuytren's disease ( 21732829) Fasting insulin-related traits (interaction with BMI) ( 22581228) Height ( 21998595)
Protein-protein Interactions		2 interactors: APP NEDD4
Entrez ID		23213
HPRD ID		15450
Ensembl ID		ENSG00000137573
Uniprot IDs		Q8IWU6
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuromuscular Junction Development Regulation Of Synapse Structure Or Activity Synapse Organization Intracellular Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Synaptic Growth At Neuromuscular Junction Response To Light Stimulus Collateral Sprouting In Absence Of Injury Response To Radiation Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Progesterone Receptor Signaling Pathway Axon Choice Point Recognition Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Regulation Of Neuron Differentiation Glucocorticoid Receptor Signaling Pathway Neuron Remodeling Endocytosis Cell Activation Regulation Of Neurogenesis Protein Targeting To Lysosome Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein Localization To Lysosome Neuron Projection Development Regulation Of Cell Development Cellular Copper Ion Homeostasis Receptor Catabolic Process Neuron Development Protein Targeting To Vacuole Copper Ion Homeostasis Suckling Behavior Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Establishment Of Protein Localization To Vacuole Response To Abiotic Stimulus Neuron Differentiation Regulation Of Potassium Ion Transmembrane Transporter Activity Cell Projection Organization Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cell Adhesion Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein K63-linked Ubiquitination Positive Regulation Of Protein Metabolic Process Mating Behavior
Tagcloud ?		abcc8 acacb cacna1a camk2d cdkal1 chi csmd1 disequilibrium exome glud1 gnas hnf1a hyperinsulinism kcnh6 kcnj10 kcnj11 nos2 notch2 pde4c pik3r3 probands ryr3 scn8a slc24a6 slc37a3 tdt tll1 trpc5 trpv3