KDM4C

Gene Name		lysine (K)-specific demethylase 4C
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Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm
	Molecular Function	Zinc Ion Binding Enzyme Binding Histone Demethylase Activity (H3-K9 Specific) Androgen Receptor Binding Dioxygenase Activity
	Biological Process	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Histone H3-K9 Demethylation Oxidation-reduction Process
Pathways		Chromatin modifying enzymes Chromatin organization HDMs demethylate histones
Drugs
Diseases
GWAS		Radiation response ( 20923822) Response to fenofibrate (adiponectin levels) ( 23149075)
Protein-protein Interactions		2 interactors: HIST1H3A HIST2H3C
Entrez ID		23081
HPRD ID		12016
Ensembl ID		ENSG00000107077
Uniprot IDs		B4E142 B4E239 B7Z3V6 C9J879 Q9H3R0
PDB IDs		2XDP 2XML
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Chromatin Silencing At RDNA Chromatin Silencing DNA Methylation Negative Regulation Of Gene Expression, Epigenetic DNA Modification Gene Silencing Regulation Of Gene Expression, Epigenetic Methylation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing DNA Replication-dependent Nucleosome Assembly Response To Wounding Regulation Of Gene Silencing DNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Nucleosome Assembly Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Response To Stress Gene Expression DNA Conformation Change
Tagcloud ?		1alpha 2alpha 6b catalyzes cocl2 demethylase demethylases demethylation desferrioxamine dimethylation elongation experiment h3k27 h3k27me3 hif hypoxia immunoprecipitation implies indicates kdm3a kdm4b kdm6b lysine mesylate mimic modestly o2 rnai tri