MYO16

Description		myosin XVI
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Myosin Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding ATP Binding Protein Phosphatase Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Cerebellum Development Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Neuron Projection Morphogenesis Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease ( 30636644) Alzheimer's disease (cognitive decline) ( 23535033) Blood pressure ( 22763476) Chronotype ( 30696823) Colorectal cancer ( 29228715) Dental caries ( 23064961) Eosinophil count ( 32888494) Femur bone mineral density x serum urate levels interaction ( 34046847) Ferritin levels ( 33491795) Lung function (FEV1/FVC) ( 30804560) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494) Nose size ( 27182965) Obesity-related traits ( 23251661) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Presence of antiphospholipid antibodies ( 23509613) Red blood cell count ( 27863252 32888494) Red cell distribution width ( 32888494) Resting-state electroencephalogram vigilance ( 29703947) Seasonality ( 25562672) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Novel Interacting Genes		1 novel interacting genes: DAOA
Interacting Genes		6 interacting genes: CYFIP1 NCKAP1 NRXN1 PIK3R1 PPP1CA PPP1CC
Entrez ID		23026
HPRD ID		14795
Ensembl ID		ENSG00000041515
Uniprot IDs		F8W883 Q9Y6X6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Lamellipodium Assembly Regulation Of Lamellipodium Assembly Positive Regulation Of Lamellipodium Organization Regulation Of Cell Projection Assembly Regulation Of Lamellipodium Organization Postsynapse PTW/PP1 Phosphatase Complex Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation SCAR Complex Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Actin Nucleation Positive Regulation Of Cellular Component Organization Positive Regulation Of Cellular Component Biogenesis Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding Rac Protein Signal Transduction Photoperiodism Entrainment Of Circadian Clock Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Protein Stabilization Presynapse Lamellipodium Assembly Regulation Of Actin Nucleation Regulation Of Actin Filament Organization Lamellipodium Organization Regulation Of Filopodium Assembly Intracellular Signaling Cassette Response To Light Stimulus Glycogen Metabolic Process Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Stability Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cell Projection Organization Regulation Of Actin Filament-based Process Circadian Regulation Of Gene Expression Energy Reserve Metabolic Process Phosphatase Activity Polysaccharide Metabolic Process Positive Regulation Of Presynaptic Active Zone Assembly Positive Regulation Of Presynapse Assembly Positive Regulation Of CAMP-mediated Signaling Protein-containing Complex Assembly Involved In Synapse Maturation Focal Adhesion Positive Regulation Of Protein Localization To Membrane Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity
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