RAB21

Description		RAB21, member RAS oncogene family
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GO Annotations	Cellular Component	Golgi Membrane Endosome Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Focal Adhesion Cytoplasmic Side Of Plasma Membrane Endomembrane System Vesicle Membrane Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Cleavage Furrow Golgi Cisterna Membrane Cell Projection Neuron Projection Synapse Extracellular Exosome Cytoplasmic Side Of Early Endosome Membrane Axon Cytoplasm
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding
	Biological Process	Intracellular Protein Transport Anterograde Axonal Transport Protein Transport Regulation Of Exocytosis Regulation Of Axon Extension Rab Protein Signal Transduction Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Dendrite Morphogenesis Protein Stabilization Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways		RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Adult body size ( 32376654) Apolipoprotein B levels ( 32203549) Body mass index ( 29273807) General cognitive ability ( 29844566) HDL cholesterol levels ( 32759990) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731)
Interacting Genes		1 interacting genes: APPL1
Entrez ID		23011
HPRD ID		06695
Ensembl ID		ENSG00000080371
Uniprot IDs		Q9UL25
PDB IDs		1YZT 1YZU 1Z08 1Z0I 2OT3
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macropinocytosis Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Melanin Biosynthetic Process Positive Regulation Of Pinocytosis Early Phagosome Positive Regulation Of Melanin Biosynthetic Process Macropinosome Cellular Response To Hepatocyte Growth Factor Stimulus Protein Kinase B Binding Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Adiponectin-activated Signaling Pathway Response To Hepatocyte Growth Factor Intracellular Vesicle Negative Regulation Of Phagocytosis Maintenance Of Synapse Structure Positive Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of D-glucose Import Vesicle Membrane Regulation Of Fibroblast Migration Beta-tubulin Binding Positive Regulation Of D-glucose Transmembrane Transport Cell Junction Maintenance Phosphatidylserine Binding Regulation Of D-glucose Import Cellular Component Maintenance Negative Regulation Of Endocytosis Regulation Of D-glucose Transmembrane Transport Regulation Of Cytokine Production Involved In Inflammatory Response Insulin Receptor Signaling Pathway Phagocytic Vesicle Regulation Of Phagocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Ruffle Phosphatidylinositol Binding Regulation Of Protein Localization To Plasma Membrane Protein Import Into Nucleus Import Into Nucleus Hormone-mediated Signaling Pathway Positive Regulation Of Endocytosis Regulation Of Protein Localization To Cell Periphery Regulation Of G1/S Transition Of Mitotic Cell Cycle Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Protein Localization To Nucleus Regulation Of Protein Localization To Membrane Regulation Of Cell Cycle G1/S Phase Transition Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Early Endosome Membrane Nuclear Transport Nucleocytoplasmic Transport
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