FOXF1

Description		forkhead box F1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Blood Vessel Development Vasculogenesis In Utero Embryonic Development Somitogenesis Morphogenesis Of A Branching Structure Positive Regulation Of Mesenchymal Cell Proliferation Endocardial Cushion Development Cardiac Left Ventricle Morphogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Smoothened Signaling Pathway Determination Of Left/right Symmetry Midgut Development Mesoderm Development Heart Development Animal Organ Morphogenesis Positive Regulation Of Cell-substrate Adhesion Detection Of Wounding Extracellular Matrix Organization Respiratory Tube Development Lung Development Positive Regulation Of Cell Migration Pancreas Development Negative Regulation Of Mast Cell Degranulation Establishment Of Epithelial Cell Apical/basal Polarity Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Lung Alveolus Development Mesodermal Cell Differentiation Lateral Mesodermal Cell Differentiation Embryonic Digestive Tract Morphogenesis Digestive Tract Development Embryonic Digestive Tract Development Embryonic Ectodermal Digestive Tract Morphogenesis Embryonic Foregut Morphogenesis System Development Negative Regulation Of Inflammatory Response Smooth Muscle Cell Differentiation Lung Morphogenesis Lung Vasculature Development Trachea Development Epithelial Tube Branching Involved In Lung Morphogenesis Right Lung Morphogenesis Lung Lobe Morphogenesis Venous Blood Vessel Development Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Cellular Response To Cytokine Stimulus Ureter Development Mesenchyme Migration Ductus Arteriosus Closure Cell-cell Adhesion
Pathways		Formation of lateral plate mesoderm Regulation of CDH11 gene transcription
Drugs
Diseases		Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV)
GWAS		Aspartate aminotransferase levels ( 33547301) Barrett's esophagus ( 22961001) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Breast cancer (survival) ( 25526632) Corneal astigmatism ( 23322567) Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined) ( 24121790) Esophageal adenocarcinoma ( 24121790) Nonsyndromic cleft palate ( 31609978) Obesity (early onset extreme) ( 23563609) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549)
Interacting Genes		2 interacting genes: AURKA UBC
Entrez ID		2294
HPRD ID		03053
Ensembl ID		ENSG00000103241
Uniprot IDs		Q12946
PDB IDs
Enriched GO Terms of Interacting Partners?		Spindle Assembly Involved In Female Meiosis I Pronucleus Germinal Vesicle Chromosome Passenger Complex Ubiquitin Protein Ligase Binding Mitotic Centrosome Separation Histone H3S10 Kinase Activity Axon Hillock Positive Regulation Of Oocyte Maturation Meiotic Spindle Cilium Disassembly Modification-dependent Protein Catabolic Process Centrosome Separation Spindle Assembly Involved In Female Meiosis Meiotic Spindle Assembly Spindle Pole Centrosome Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Cell Maturation Protein Tag Activity Meiotic Spindle Organization Positive Regulation Of Mitochondrial Fission Regulation Of Cell Maturation Molecular Function Activator Activity Protein Localization To Centrosome Spindle Midzone Protein Serine/threonine/tyrosine Kinase Activity Liver Regeneration Regulation Of Mitochondrial Fission Negative Regulation Of Protein Binding Macromolecule Catabolic Process Centrosome Localization Peptidyl-serine Phosphorylation Spindle Microtubule Anterior/posterior Axis Specification Regulation Of Protein Binding Mitotic Spindle Pole Proteolysis Protein Localization To Cytoskeleton Centrosome Cycle Positive Regulation Of Mitotic Nuclear Division G2/M Transition Of Mitotic Cell Cycle Animal Organ Regeneration Cell Cycle G2/M Phase Transition Regulation Of Centrosome Cycle Protein Modification Process Organelle Disassembly Positive Regulation Of Reproductive Process Axis Specification Endocytic Vesicle Membrane Neuron Projection Extension
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