AAK1

Gene Name		AP2 associated kinase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Coated Pit Extrinsic Component Of Plasma Membrane Clathrin-coated Vesicle Cell Leading Edge Terminal Bouton
	Molecular Function	Protein Serine/threonine Kinase Activity Notch Binding Protein Binding ATP Binding AP-2 Adaptor Complex Binding
	Biological Process	Protein Phosphorylation Endocytosis Regulation Of Protein Localization Positive Regulation Of Notch Signaling Pathway Protein Autophosphorylation Protein Stabilization Regulation Of Clathrin-mediated Endocytosis
Pathways
Drugs
Diseases
GWAS		Parkinson's disease (age of onset) ( 19772629)
Protein-protein Interactions		1 interactors: APP
Entrez ID		22848
HPRD ID		10620
Ensembl ID
Uniprot IDs		Q2M2I8
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing Cholesterol Metabolic Process Adult Locomotory Behavior Positive Regulation Of Mitotic Cell Cycle Regulation Of Receptor Activity Cell Recognition
Tagcloud ?		1a 1b 2vo alleviated aminobutyric ap2 baclofen ca1 collateral gaba gabab hcn hcn1 hcn2 hyperpolarization hypoperfusion mu2 mutually nonselective nonspatial pathologically phosphorylating pka r1 r2 rab8b schaffer tpr trip8b