PPM1E

Gene Name		protein phosphatase, Mg2+/Mn2+ dependent, 1E
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Mitochondrion Protein Complex
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Cellular Response To Drug Peptidyl-threonine Dephosphorylation Positive Regulation Of Stress Fiber Assembly
Pathways
Drugs
Diseases
GWAS		Circulating myeloperoxidase levels (plasma) ( 23620142) Cognitive test performance ( 17903297) Testicular germ cell tumor ( 23666239)
Protein-protein Interactions		4 interactors: ARHGEF7 DISC1 GAPDH TNIK
Entrez ID		22843
HPRD ID		17888
Ensembl ID
Uniprot IDs		A7E2X1 Q8WY54
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Projection Organization Peptidyl-cysteine S-trans-nitrosylation Regulation Of Cell Development Cytoskeleton Organization Positive Regulation Of Lamellipodium Morphogenesis Peptidyl-cysteine S-nitrosylation Wnt Signaling Pathway Cell Projection Assembly Regulation Of Lamellipodium Morphogenesis Generation Of Neurons Regulation Of Cell Differentiation Neurogenesis Activation Of JNKK Activity Regulation Of Neuron Projection Development Positive Regulation Of Fibroblast Migration Intracellular Signal Transduction Microtubule Cytoskeleton Organization Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Morphogenesis Microvillus Assembly Positive Regulation Of Cell Development Microvillus Organization Mitochondrial Calcium Ion Homeostasis Regulation Of Protein Metabolic Process Positive Regulation Of Lamellipodium Organization Regulation Of Neuron Differentiation Regulation Of Synapse Maturation Nervous System Development TOR Signaling Positive Regulation Of Neuroblast Proliferation Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Neurogenesis Focal Adhesion Assembly Regulation Of Fibroblast Migration Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Signal Transduction Microtubule-based Process Cellular Response To Stimulus Lamellipodium Assembly Positive Regulation Of Cell Differentiation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Adherens Junction Assembly Regulation Of Signaling Lamellipodium Organization Negative Regulation Of ERBB Signaling Pathway Positive Regulation Of Protein Modification Process Cell Surface Receptor Signaling Pathway Cell Proliferation In Forebrain Organelle Organization
Tagcloud ?		2c ac acetylated aging alters bipolar decarboxylase gad1 glutamic h3k9k14 hdac homolog htr2c hydroxytryptamine hypoacetylation lysines marks neuropsychiatric outer postmortem prefrontal psychiatric qpcr schizophrenia tomm70a transcriptionally translocase whereby